{"id":"W4388732355","doi":"10.3390/molecules28227619","title":"Anti-Inflammatory Properties of Eugenol in Lipopolysaccharide-Induced Macrophages and Its Role in Preventing β-Cell Dedifferentiation and Loss Induced by High Glucose-High Lipid Conditions","year":2023,"lang":"en","type":"article","venue":"Molecules","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Mitacs","keywords":"Inflammation; Proinflammatory cytokine; Inflammasome; Chemistry; Lipopolysaccharide; Eugenol; TLR4; Cell biology; Endocrinology; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276314,0.0003104971,0.0003242135,0.0003369187,0.0001692054,0.0002729511,0.0001543409,0.0002927258,0.0009190943],"category_scores_gemma":[0.0001114184,0.00009811466,0.0003951241,0.0002464917,0.0001535377,0.0003270148,0.0002238968,0.0006765185,0.0001150623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001075141,"about_ca_system_score_gemma":0.000179753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004765665,"about_ca_topic_score_gemma":0.0006681529,"domain_scores_codex":[0.9999297,0.00001352801,0.000009915231,0.00001419322,0.00001426417,0.00001839698],"domain_scores_gemma":[0.9999379,0.000008201807,0.0000201972,0.000006612888,0.000011841,0.00001530199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001272283,0.0002402148,0.0002290915,0.0003770392,0.00002469839,0.00009345515,0.00003617064,0.0001129265,0.9922328,0.0001093907,0.00006214251,0.005209747],"study_design_scores_gemma":[0.0001238229,0.00348056,0.008518562,0.00009803897,0.0001375021,0.0002860776,0.0001029348,0.0004934799,0.981025,0.0001889206,0.005526083,0.00001898896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977204,0.01867673,0.001758558,0.000209307,0.0001010921,0.00005289748,0.0004098947,0.00005031845,0.001537242],"genre_scores_gemma":[0.9909344,0.00521247,0.001636407,0.0001828832,0.00002210369,0.00003245864,0.0003837259,0.00001009857,0.00158543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009190943,"threshold_uncertainty_score":0.003074706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007996117290778329,"score_gpt":0.2159096893637844,"score_spread":0.207913572073006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}