{"id":"W4388738310","doi":"10.1097/01.hs9.0000936164.84357.ed","title":"P09 DARATUMUMAB PLUS LENALIDOMIDE AND DEXAMETHASONE (D-RD) VERSUS LENALIDOMIDE AND DEXAMETHASONE (RD) ALONE IN TRANSPLANT-INELIGIBLE PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA (NDMM): UPDATED ANALYSIS OF THE PHASE 3 MAIA STUDY","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"","keywords":"Lenalidomide; Medicine; Daratumumab; Internal medicine; Multiple myeloma; Clinical endpoint; Dexamethasone; Surgery; Phases of clinical research; Minimal residual disease; Progression-free survival; Oncology; Gastroenterology; Chemotherapy; Randomized controlled trial; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005611796,0.0005459,0.001451804,0.0005686247,0.0002262008,0.00005996241,0.0002423202,0.0001749396,0.0002036701],"category_scores_gemma":[0.0004816755,0.0003662652,0.0001941734,0.003455868,0.0002914492,0.0002100421,0.0001666342,0.0004423615,0.00001445025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001873896,"about_ca_system_score_gemma":0.0001936998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003351879,"about_ca_topic_score_gemma":0.0136797,"domain_scores_codex":[0.9960263,0.0004183888,0.0007556024,0.0009146354,0.001046766,0.0008382613],"domain_scores_gemma":[0.9970499,0.001153912,0.0002618777,0.00085045,0.000227707,0.0004562094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03794546,0.002424846,0.9437218,0.0001778006,0.004412899,0.0009315512,0.002054717,0.0003600045,0.001303138,0.000004092806,0.0003660552,0.006297625],"study_design_scores_gemma":[0.1801837,0.001853013,0.8013242,0.000264258,0.00278524,0.00001190155,0.002291368,0.007571246,0.003234639,0.000007061163,0.0001023941,0.0003709447],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955875,0.0006758022,0.00006517743,0.0002725337,0.00007434004,0.002708817,0.0003834384,0.00009311862,0.0001393058],"genre_scores_gemma":[0.9976153,0.0002895649,0.0008342122,0.00004867183,0.00003023844,0.0002115549,0.0006370769,0.00007398318,0.0002593512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1423975,"threshold_uncertainty_score":0.9998789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02799922324280263,"score_gpt":0.3080481877675247,"score_spread":0.2800489645247221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}