{"id":"W4388751240","doi":"10.1016/j.bpsc.2023.10.011","title":"The Toronto Adolescent and Youth Cohort Study: Study Design and Early Data Related to Psychosis Spectrum Symptoms, Functioning, and Suicidality","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry Cognitive Neuroscience and Neuroimaging","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Guelph; Mental Health Research Canada; Centre for Addiction and Mental Health","funders":"Department of Psychiatry, Faculty of Medicine, University of British Columbia; Canadian Institutes of Health Research; National Institute of Mental Health; Social Sciences and Humanities Research Council of Canada; Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health; Department of Psychiatry, University of Toronto; Peter Gilgan Foundation; Cundill Centre for Child and Youth Depression; Canadian Institute for Military and Veteran Health Research; Hospital for Sick Children; University of Toronto; Canada Research Chairs; Koninklijke Nederlandse Akademie van Wetenschappen; Canarie; Ontario Brain Institute; Arcus Foundation; Fondation Brain Canada; Rainwater Charitable Foundation; Ontario HIV Treatment Network; Azrieli Foundation; Natural Sciences and Engineering Research Council of Canada; Ministère de la Défense Nationale; Centre for Addiction and Mental Health Foundation; Government of Ontario; Krembil Foundation; Canada Foundation for Innovation; Novartis Foundation; CurePSP; Royal Bank of Canada; Centre for Addiction and Mental Health; Wellcome Trust; Heart and Stroke Foundation of Canada; J.W. McConnell Family Foundation; Ontario Research Foundation; National Institutes of Health; Robert Wood Johnson Foundation","keywords":"Psychosis; Psychiatry; Cohort; Psychology; Medicine; Clinical psychology; Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001120103,0.0002418907,0.0002789172,0.00007690892,0.000870886,0.0002682791,0.0001613429,0.00003649266,0.000002457383],"category_scores_gemma":[0.0005081188,0.0001458327,0.00002073528,0.0004126295,0.0004583193,0.0001879917,0.0005544276,0.0002738312,0.000003115839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001557666,"about_ca_system_score_gemma":0.00004366446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002585861,"about_ca_topic_score_gemma":0.0001322783,"domain_scores_codex":[0.997171,0.0004494947,0.0002605508,0.001318963,0.0003393412,0.0004606651],"domain_scores_gemma":[0.9988334,0.0003034972,0.0000606907,0.0003640217,0.00004721651,0.0003912149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001450444,0.000422007,0.9913352,0.000005134599,0.00003024352,0.00003955789,0.0002867062,1.005313e-7,0.0001493329,0.00002143549,0.00004785743,0.006211983],"study_design_scores_gemma":[0.00223045,0.005174275,0.9888547,0.00003918154,0.0001296066,0.00005151557,0.00302087,0.000196312,0.000005697831,0.0001356596,0.00001499114,0.0001467363],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932762,0.0009831943,0.00004824308,0.002482538,0.0003279066,0.002710086,0.00002917432,0.0001081964,0.00003442609],"genre_scores_gemma":[0.9978898,0.001293449,0.00003317857,0.0006348591,0.0000444551,0.00005421524,0.000006892026,0.00001320839,0.00002992531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006065247,"threshold_uncertainty_score":0.6698239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09995277479766308,"score_gpt":0.3640016290658867,"score_spread":0.2640488542682236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}