{"id":"W4388760389","doi":"10.3233/jnd-230178","title":"Findings from the Longitudinal CINRG Becker Natural History Study","year":2023,"lang":"en","type":"article","venue":"Journal of Neuromuscular Diseases","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; University of Calgary","funders":"National Institutes of Health; Newcastle University; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Children's National Hospital; Children's Healthcare of Atlanta; University of Minnesota; University of Pittsburgh; Muscular Dystrophy Association; U.S. Department of Veterans Affairs","keywords":"Medicine; Natural history; Muscular dystrophy; Natural history study; Cohort; Longitudinal study; Cohort study; Clinical trial; Internal medicine; Family history; Pediatrics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375015,0.0001404935,0.0001744475,0.00005179994,0.0001026803,0.00001529347,0.0003629595,0.00004653615,0.00006304681],"category_scores_gemma":[0.0002861337,0.00009501707,0.0003046214,0.0001004466,0.000101695,0.000009852821,0.0001241039,0.0001807662,0.00001838492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001584506,"about_ca_system_score_gemma":0.0001043237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001710022,"about_ca_topic_score_gemma":0.0000154743,"domain_scores_codex":[0.9989409,0.0001840545,0.0002389247,0.0002162901,0.0002380738,0.0001817554],"domain_scores_gemma":[0.9993134,0.00006604079,0.0001349943,0.0003053789,0.0000891063,0.00009106839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001234929,0.0008509858,0.5959779,0.00001879689,0.0008612319,0.0004293125,0.0004134114,0.0003033178,0.1556757,0.00001590208,0.2431725,0.001046004],"study_design_scores_gemma":[0.000810032,0.0004532985,0.9796451,0.000009072252,0.0001675322,0.00001185543,0.0003356799,0.00001570868,0.0002556957,0.00007957144,0.01810061,0.0001158182],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929634,0.005686002,0.000008188172,0.0003821227,0.0007964956,0.0001138766,0.00001429637,0.00001111433,0.00002447871],"genre_scores_gemma":[0.998445,0.0002318179,0.000005886808,0.0006931874,0.00043448,0.000005269115,0.00004001953,0.00001806509,0.0001262194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3836672,"threshold_uncertainty_score":0.3874683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01854655592393398,"score_gpt":0.2539601929615071,"score_spread":0.2354136370375731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}