{"id":"W4388765587","doi":"10.1016/j.ijrobp.2023.11.006","title":"Randomized Trial of Concomitant Hypofractionated Intensity Modulated Radiation Therapy Boost Versus Conventionally Fractionated Intensity Modulated Radiation Therapy Boost for Localized High-Risk Prostate Cancer (pHART2-RCT)","year":2023,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; University Health Network; University of Toronto; Health Sciences Centre","funders":"","keywords":"Randomized controlled trial; Prostate cancer; Medicine; Oncology; Concomitant; Radiation therapy; Internal medicine; Intensity (physics); Cancer; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002494663,0.003110964,0.005468033,0.0004966171,0.0007151425,0.001820179,0.001896884,0.002918767,0.01903067],"category_scores_gemma":[0.003834443,0.001762338,0.00343343,0.0006259379,0.001896376,0.001907154,0.001033542,0.005392488,0.002600617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001309858,"about_ca_system_score_gemma":0.001899851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002805374,"about_ca_topic_score_gemma":0.003832358,"domain_scores_codex":[0.9984445,0.0008242274,0.0001111163,0.0003706887,0.0000745115,0.0001749275],"domain_scores_gemma":[0.99804,0.0006055952,0.0003941516,0.0003135212,0.0001164603,0.0005301952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9961196,0.001059293,0.00006989365,0.0001654682,0.0005759604,0.000006822084,0.00001403234,0.0001471986,0.0003948018,0.00004420076,0.0001347663,0.001267973],"study_design_scores_gemma":[0.9747624,0.0232781,0.0004609552,0.00002399123,0.0006580844,0.00001184218,0.00001240065,0.0002869872,0.0001461816,0.0001300847,0.0002175367,0.00001150257],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798322,0.004249627,0.001490997,0.001007761,0.001918454,0.005093555,0.002031323,0.0003403587,0.004035785],"genre_scores_gemma":[0.9777963,0.001763009,0.003231932,0.001288909,0.0009748045,0.005157636,0.001631529,0.0001002606,0.008055679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01903067,"threshold_uncertainty_score":0.0636639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03627974587182227,"score_gpt":0.3530294701029434,"score_spread":0.3167497242311211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}