{"id":"W4388781469","doi":"10.1016/j.fander.2023.09.072","title":"Efficacité et sécurité d’emploi de l’avapritinib dans la mastocytose systémique indolente (MSI) : résultats de l’étude PIONEER en double aveugle, contrôlée par placebo","year":2023,"lang":"fr","type":"article","venue":"Annales de Dermatologie et de Vénéréologie - FMC","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002054505,0.0006828977,0.002042719,0.0003638954,0.0002678569,0.0005379946,0.0005368771,0.001218683,0.003418637],"category_scores_gemma":[0.001531809,0.0004014242,0.00166207,0.0002543729,0.000657675,0.001002151,0.0001636664,0.001505791,0.0005752106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004751379,"about_ca_system_score_gemma":0.0003001435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001055071,"about_ca_topic_score_gemma":0.001056529,"domain_scores_codex":[0.9990475,0.0003983279,0.00008476168,0.0001735363,0.0001563877,0.0001395333],"domain_scores_gemma":[0.9991536,0.0003982054,0.0001582396,0.0001009505,0.00008519609,0.0001038058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6461495,0.02282964,0.004280698,0.001738086,0.002704755,0.0002638131,0.0003737279,0.001191355,0.1207399,0.0001847201,0.001236072,0.1983078],"study_design_scores_gemma":[0.1522382,0.7467822,0.03727025,0.0001022343,0.004949523,0.0007158222,0.0001342169,0.001642736,0.04970428,0.0001752706,0.006188825,0.00009627263],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817738,0.01481482,0.000712201,0.0002366813,0.0001849649,0.000384801,0.0004863417,0.0000608045,0.001345527],"genre_scores_gemma":[0.9923263,0.003695227,0.0007304958,0.0001717882,0.0002261262,0.0002421008,0.0004558183,0.00001792649,0.002134265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003418637,"threshold_uncertainty_score":0.01143646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0275223928256183,"score_gpt":0.3017844539645633,"score_spread":0.274262061138945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}