{"id":"W4388796304","doi":"10.1038/s41598-023-47573-z","title":"The role of specific isoforms of CaV2 and the common C-terminal of CaV2 in calcium channel function in sensory neurons of Aplysia","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aplysia; Neuroscience; Habituation; R-type calcium channel; Biology; Sensory system; Protein subunit; Synapse; Synaptic fatigue; Voltage-dependent calcium channel; Cell biology; T-type calcium channel; Chemistry; Calcium; Biochemistry; Excitatory postsynaptic potential; Gene; Inhibitory postsynaptic potential","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293544,0.0002355635,0.0002117925,0.0002698139,0.0001991097,0.000340523,0.0002183147,0.0003288218,0.0006332349],"category_scores_gemma":[0.0002442586,0.0001688049,0.000286783,0.0001571834,0.0002953238,0.0002496723,0.0002473092,0.0004696455,0.0001955512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003673799,"about_ca_system_score_gemma":0.0002056475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000660456,"about_ca_topic_score_gemma":0.0008528941,"domain_scores_codex":[0.9998618,0.00001511568,0.00002660541,0.00004222898,0.00002803482,0.00002626537],"domain_scores_gemma":[0.9997994,0.00002951384,0.00005968389,0.00002321243,0.00002380137,0.00006428545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006643043,0.000005671768,0.0004232766,0.00001002888,0.000002926699,0.0000650492,0.00001208063,0.00002454714,0.9991792,0.00004497717,0.000007264569,0.0001584763],"study_design_scores_gemma":[0.00007955561,0.0003611071,0.1390578,0.00002122453,0.00006397278,0.002739585,0.0002745418,0.003530902,0.8513043,0.0002333246,0.002310615,0.00002299676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989552,0.0001783684,0.0004885187,0.00002377764,0.000007663619,0.000004948604,0.0001250666,0.000009047241,0.0002072708],"genre_scores_gemma":[0.9981691,0.00009532208,0.0006755085,0.00003938461,0.000005352041,0.00001742903,0.0004282981,0.00001140279,0.0005583205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000660456,"threshold_uncertainty_score":0.00266552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03593141132822122,"score_gpt":0.2873120323342737,"score_spread":0.2513806210060524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}