{"id":"W4388829778","doi":"10.1007/s00198-023-06843-2","title":"Proposed diagnostic criteria for the diagnosis of hypophosphatasia in children and adolescents: results from the HPP International Working Group","year":2023,"lang":"en","type":"review","venue":"Osteoporosis International","topic":"Alkaline Phosphatase Research Studies","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Manitoba; Hamilton Health Sciences; McMaster University Medical Centre; Children's Hospital of Eastern Ontario; Impact; Université de Sherbrooke; McMaster University","funders":"","keywords":"Hypophosphatasia; Medicine; Inborn error of metabolism; MEDLINE; Pediatrics; Natural history; Internal medicine; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03337426,0.00173701,0.003853492,0.03116359,0.001016541,0.004016179,0.003917338,0.002474675,0.002529955],"category_scores_gemma":[0.07909348,0.0007448636,0.006627418,0.0207942,0.001679898,0.003446317,0.002929606,0.001836097,0.001146759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005428887,"about_ca_system_score_gemma":0.01500942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008490316,"about_ca_topic_score_gemma":0.01103214,"domain_scores_codex":[0.9789765,0.004588525,0.01052704,0.001060531,0.004313048,0.0005343682],"domain_scores_gemma":[0.9261124,0.04042878,0.008851245,0.001162574,0.02262151,0.0008235398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000606164,0.0001371922,0.05635628,0.2806272,0.003896048,0.001883986,0.003744714,0.0009614049,0.001492696,0.006014152,0.04471051,0.5995696],"study_design_scores_gemma":[0.0007768098,0.0005226125,0.1207138,0.4743807,0.02697168,0.01026217,0.005858941,0.001732275,0.002211172,0.005965002,0.3502803,0.0003246631],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00761713,0.9627914,0.004585799,0.01011238,0.001207687,0.002490989,0.003959728,0.00008020185,0.007154748],"genre_scores_gemma":[0.07203457,0.8475565,0.05512121,0.005346697,0.0009969089,0.005504461,0.0122202,0.0000564514,0.001162926],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03337426,"threshold_uncertainty_score":0.1765021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07659599003612504,"score_gpt":0.3853712529318619,"score_spread":0.3087752628957368,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}