{"id":"W4388835034","doi":"10.1001/jamainternmed.2023.6256","title":"Therapeutic Benefit From New Drugs From Pharmaceutical Companies","year":2023,"lang":"en","type":"letter","venue":"JAMA Internal Medicine","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; York University","funders":"","keywords":"Medicine; Otorhinolaryngology; Family medicine; Neurology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002535262,0.0004874381,0.0006538483,0.0008863309,0.003100981,0.004166206,0.0007483267,0.03098297,0.07467175],"category_scores_gemma":[0.02995754,0.0004132852,0.000965426,0.001008027,0.001779751,0.003481568,0.001583351,0.01285654,0.03960845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003544339,"about_ca_system_score_gemma":0.005794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004152336,"about_ca_topic_score_gemma":0.009088726,"domain_scores_codex":[0.9971715,0.0005072241,0.0002314211,0.0002654393,0.001424402,0.0004000134],"domain_scores_gemma":[0.9906906,0.005927766,0.0004362681,0.0005541475,0.001199345,0.001191963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003590824,0.00004164897,0.0004602668,0.00004964069,0.000007335331,0.0007277862,0.00003006149,0.00006465149,0.0001027382,0.009266483,0.9737446,0.01546884],"study_design_scores_gemma":[0.0001023881,0.00005019579,0.001682443,0.0002307331,0.00001098125,0.001351663,0.00005245145,0.0003943911,0.0001743215,0.009963661,0.9859676,0.00001920248],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001794051,0.003434704,0.0003970934,0.7003911,0.01118738,0.00006687672,0.0003568972,0.000234332,0.2821375],"genre_scores_gemma":[0.03145083,0.003534362,0.0007216844,0.7277468,0.03983136,0.0001501593,0.0002348924,0.0001158374,0.1962141],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07467175,"threshold_uncertainty_score":0.2498019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108191530576531,"score_gpt":0.3272168631452734,"score_spread":0.2190253325687424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}