{"id":"W4388848294","doi":"10.15690/pf.v20i5.2646","title":"Glycogen storage disease type Ib: modern understanding of the pathogenesis of neutropenia and prospects for its treatment with empagliflozin","year":2023,"lang":"en","type":"article","venue":"Педиатрическая фармакология","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute","funders":"","keywords":"Medicine; Hypoglycemia; Glycogen storage disease type I; Neutropenia; Glycogen storage disease; Internal medicine; Hyperuricemia; Gastroenterology; Type 2 diabetes; Lactic acidosis; Metformin; Endocrinology; Ketoacidosis; Diabetes mellitus; Insulin; Immunology; Glycogen; Type 1 diabetes; Uric acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001099928,0.0002771624,0.0005056083,0.0001348201,0.0001510013,0.00001679176,0.0001281961,0.00006893023,0.00002134535],"category_scores_gemma":[0.00006934096,0.0001721205,0.0002045016,0.0005400663,0.0001345804,0.00006986011,0.00008187092,0.00005899768,0.000005024317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000159536,"about_ca_system_score_gemma":0.0003736948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003068109,"about_ca_topic_score_gemma":0.0000331247,"domain_scores_codex":[0.998509,0.00004197234,0.0003106463,0.000415614,0.0003607449,0.0003620462],"domain_scores_gemma":[0.9986937,0.00008229031,0.0001957525,0.0005341387,0.0001944547,0.0002996315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.04729699,0.004000763,0.2783706,0.009487788,0.004574886,0.004479387,0.009718925,0.002360043,0.6013567,0.01766248,0.003108586,0.01758287],"study_design_scores_gemma":[0.05331776,0.01992414,0.7537942,0.004110015,0.01690748,0.0005932727,0.006753931,0.04301012,0.08135419,0.005725393,0.01144363,0.003065878],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942358,0.002278525,0.0002812851,0.000432857,0.0001522649,0.001930072,0.000416311,0.00007594976,0.0001969614],"genre_scores_gemma":[0.9978743,0.0002304389,0.0001737082,0.00007656013,0.00008358937,0.0001120744,0.00006020103,0.00007025037,0.001318882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5200025,"threshold_uncertainty_score":0.7018869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05273343503473528,"score_gpt":0.2768239631614634,"score_spread":0.2240905281267281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}