{"id":"W4388848294","doi":"10.15690/pf.v20i5.2646","title":"Glycogen storage disease type Ib: modern understanding of the pathogenesis of neutropenia and prospects for its treatment with empagliflozin","year":2023,"lang":"en","type":"article","venue":"Педиатрическая фармакология","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute","funders":"","keywords":"Medicine; Hypoglycemia; Glycogen storage disease type I; Neutropenia; Glycogen storage disease; Internal medicine; Hyperuricemia; Gastroenterology; Type 2 diabetes; Lactic acidosis; Metformin; Endocrinology; Ketoacidosis; Diabetes mellitus; Insulin; Immunology; Glycogen; Type 1 diabetes; Uric acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005977061,0.0004504235,0.0008244583,0.0008980215,0.0001398858,0.0006111224,0.0004135234,0.0006347217,0.001215731],"category_scores_gemma":[0.0004849427,0.0001382105,0.0005198477,0.0005527099,0.0003693512,0.001050623,0.0003717857,0.001751917,0.0003844975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003956567,"about_ca_system_score_gemma":0.0004097125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004572882,"about_ca_topic_score_gemma":0.0005785614,"domain_scores_codex":[0.9998724,0.00003313216,0.00002103223,0.00002320386,0.00003143415,0.00001871084],"domain_scores_gemma":[0.9998211,0.0000692816,0.00003408308,0.00001143474,0.00003822709,0.00002587877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001053962,0.0003552342,0.002067598,0.0034348,0.0001610836,0.001023963,0.00009689864,0.0009468578,0.005695278,0.008575805,0.0201213,0.9564673],"study_design_scores_gemma":[0.0007783489,0.002265919,0.01946182,0.005265807,0.0007889814,0.01388044,0.000283335,0.005768292,0.005588483,0.02787637,0.917874,0.0001682495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.004721179,0.9858406,0.001790488,0.005119094,0.0003469003,0.000009870657,0.00003817754,0.00003241109,0.002101287],"genre_scores_gemma":[0.03298068,0.9554242,0.0035934,0.003622554,0.002782871,0.00004604074,0.0001641099,0.00001189795,0.001374365],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001215731,"threshold_uncertainty_score":0.004067004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05273343503473528,"score_gpt":0.2768239631614634,"score_spread":0.2240905281267281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}