{"id":"W4388856496","doi":"10.3390/toxics11120948","title":"Case-Control Study of the Association between Single Nucleotide Polymorphisms of Genes Involved in Xenobiotic Detoxification and Antioxidant Protection with the Long-Term Influence of Organochlorine Pesticides on the Population of the Almaty Region","year":2023,"lang":"en","type":"article","venue":"Toxics","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Xenobiotic; Single-nucleotide polymorphism; Biology; Pesticide; Genetics; Detoxification (alternative medicine); Population; Genome-wide association study; Case-control study; Genotyping; Gene; Candidate gene; Genotype; Medicine; Environmental health; Internal medicine; Biochemistry; Ecology; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003715289,0.00009797904,0.0001501958,0.00003886859,0.00009090178,0.000005940006,0.0001435791,0.00007175605,5.699992e-7],"category_scores_gemma":[0.0001112396,0.00004850986,0.00004288569,0.0003330247,0.00009289436,0.000007560437,0.00003385167,0.00008488843,1.009385e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002038647,"about_ca_system_score_gemma":0.00002423896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003697474,"about_ca_topic_score_gemma":0.001006866,"domain_scores_codex":[0.9990331,0.000234529,0.0003035604,0.0001370408,0.0001954965,0.00009627111],"domain_scores_gemma":[0.9990536,0.00009918655,0.0004035631,0.0003291675,0.0001031928,0.00001128613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006539455,0.00006996921,0.554723,0.00002442068,0.00003879195,6.696035e-7,0.0002951027,0.001193615,0.4433069,0.00001966867,6.053688e-7,0.0002619518],"study_design_scores_gemma":[0.0003480729,0.0003433703,0.7088453,0.00004860434,0.0000781626,0.000005597615,0.0001557902,0.00005974678,0.2900587,0.00001830345,3.075866e-7,0.00003810261],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985191,0.00004992508,0.00007808311,0.0004119628,0.00002907291,0.0008861845,0.00001999924,0.000004223559,0.000001509344],"genre_scores_gemma":[0.9998885,0.00002592308,0.000002951824,0.0000175676,0.0000242234,0.00001443818,0.000004195286,0.0000112375,0.00001094446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1541223,"threshold_uncertainty_score":0.1978174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02014294732165611,"score_gpt":0.2245528738273181,"score_spread":0.204409926505662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}