{"id":"W4388897920","doi":"10.1139/cjpp-2023-0256","title":"Deciphering MMP9’s dual role in regulating SOD3 through protein–protein interactions","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; College of Medicine, University of Nebraska Medical Center; National Institutes of Health","keywords":"MMP9; Cell biology; Extracellular; Biology; Chemistry; Molecular biology; Biochemistry; Downregulation and upregulation; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000260112,0.0002842758,0.0002567468,0.0001550164,0.0002222107,0.0005452571,0.0002610868,0.0003835381,0.001231314],"category_scores_gemma":[0.0002119822,0.0001210695,0.0004208563,0.0001510448,0.0002271187,0.0004156411,0.0001995348,0.000721062,0.0004062173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002847657,"about_ca_system_score_gemma":0.0001986386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004201124,"about_ca_topic_score_gemma":0.0006160215,"domain_scores_codex":[0.9998127,0.00002976961,0.00001731003,0.00005400105,0.00004972609,0.00003662591],"domain_scores_gemma":[0.9998943,0.00002448426,0.00003400761,0.000009147876,0.00001968568,0.00001847851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009507315,0.00002058581,0.001131875,0.00009099376,0.00001619087,0.000166822,0.00002808288,0.00010683,0.9955205,0.0003052177,0.00008285186,0.00243516],"study_design_scores_gemma":[0.00001450273,0.00009958384,0.01601085,0.0000195211,0.00004578194,0.0005717897,0.00009350987,0.006634385,0.9686977,0.0006263528,0.007174904,0.00001116577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9628865,0.007397005,0.02605145,0.0007824407,0.0001155159,0.0000370199,0.000543236,0.0001650189,0.002021898],"genre_scores_gemma":[0.9876676,0.002312223,0.007727555,0.0001086552,0.00002694278,0.00002040726,0.0003788572,0.00002138559,0.001736345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001231314,"threshold_uncertainty_score":0.004119158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396030857785636,"score_gpt":0.2740327803499358,"score_spread":0.2600724717720795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}