{"id":"W4388901146","doi":"10.1182/blood.2023022281","title":"Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"","keywords":"Hemophagocytic lymphohistiocytosis; Medicine; Etoposide; Internal medicine; Hematopoietic stem cell transplantation; Asymptomatic; Alemtuzumab; Gastroenterology; Transplantation; Chemotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004847952,0.0001095621,0.0002405431,0.0001641787,0.0001717031,0.0005054089,0.00009944702,0.0002539321,0.00185135],"category_scores_gemma":[0.001064024,0.00003880312,0.0002485588,0.0002775931,0.0001346662,0.0003366962,0.00030133,0.0003553541,0.0003160398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000387866,"about_ca_system_score_gemma":0.000415517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006366588,"about_ca_topic_score_gemma":0.0008714828,"domain_scores_codex":[0.9998416,0.0000310416,0.00001787762,0.00003861804,0.00002639465,0.00004455986],"domain_scores_gemma":[0.9993173,0.0001024015,0.0002560849,0.00004409502,0.00006993637,0.0002101563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005762811,0.0001645246,0.9298347,0.00008153652,0.000160312,0.001072781,0.0001050574,0.0004806264,0.002651357,0.0001983853,0.002702432,0.05678543],"study_design_scores_gemma":[0.0002536907,0.002544662,0.9835078,0.00008440713,0.0001949095,0.004576449,0.0002183064,0.0006748293,0.001586313,0.000394397,0.005950928,0.00001336408],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949838,0.00235045,0.00009995201,0.0003645946,0.00005484262,0.00000551134,0.0005361714,0.000006227146,0.001598536],"genre_scores_gemma":[0.9983611,0.0004367309,0.00002451395,0.00009884193,0.00004319673,0.000002479888,0.0007775691,0.000001824966,0.0002538121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00185135,"threshold_uncertainty_score":0.006193399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01986735975431407,"score_gpt":0.2884018858684621,"score_spread":0.268534526114148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}