{"id":"W4388901146","doi":"10.1182/blood.2023022281","title":"Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"","keywords":"Hemophagocytic lymphohistiocytosis; Medicine; Etoposide; Internal medicine; Hematopoietic stem cell transplantation; Asymptomatic; Alemtuzumab; Gastroenterology; Transplantation; Chemotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004374839,0.0001455563,0.000324898,0.0003675064,0.00006651125,0.00002597958,0.0001239382,0.0001052834,0.000314268],"category_scores_gemma":[0.0001824149,0.0001372415,0.00008237974,0.0007716626,0.00002786592,0.0001246413,0.0001099204,0.0001621317,0.002614541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001272212,"about_ca_system_score_gemma":0.0003985505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008323692,"about_ca_topic_score_gemma":0.00001189874,"domain_scores_codex":[0.9983467,0.00006916264,0.0003682075,0.0003408564,0.0004644294,0.0004106736],"domain_scores_gemma":[0.9993212,0.00007369115,0.00004745232,0.0003457961,0.00008883415,0.0001229804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001042367,0.001865232,0.5477794,0.001429932,0.0005210658,0.002517314,0.005677994,0.00008052202,0.3046755,0.0001733193,0.0686994,0.06553802],"study_design_scores_gemma":[0.00624576,0.0002933118,0.929868,0.000305158,0.00007445618,0.00003064611,0.0002771296,0.0002462776,0.05172993,0.00008741763,0.01055853,0.0002833224],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870605,0.000645505,0.00001558726,0.00404912,0.0001115036,0.0005046539,0.0000115203,0.00008545228,0.007516157],"genre_scores_gemma":[0.983614,0.0004214397,0.000133882,0.001851887,0.0001752983,0.0001169179,0.0001215863,0.00004914697,0.01351589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3820887,"threshold_uncertainty_score":0.998162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01986735975431407,"score_gpt":0.2884018858684621,"score_spread":0.268534526114148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}