{"id":"W4388902110","doi":"10.2196/preprints.48576","title":"Dobutamine and Goal-Directed Fluid Therapy for Improving Tissue Oxygenation in Deep Inferior Epigastric Perforator (DIEP) Flap Breast Reconstruction Surgery: Protocol for a Randomized Controlled Trial (Preprint)","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Reconstructive Surgery and Microvascular Techniques","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"DIEP flap; Medicine; Breast reconstruction; Perioperative; Surgery; Breast cancer; Randomized controlled trial; Oxygenation; Anesthesia; Cancer; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01190189,0.003452678,0.006907694,0.001166438,0.001525438,0.00280665,0.001803093,0.003967362,0.07496249],"category_scores_gemma":[0.01575561,0.001626129,0.00445076,0.001644782,0.001719097,0.002091683,0.001047468,0.004799263,0.008558371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002496633,"about_ca_system_score_gemma":0.007559491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001508016,"about_ca_topic_score_gemma":0.002791533,"domain_scores_codex":[0.9929963,0.004003863,0.0008621275,0.0007061062,0.0006341561,0.0007974943],"domain_scores_gemma":[0.9943166,0.001620364,0.001312416,0.0007404306,0.001199906,0.0008103313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9502102,0.006333471,0.000431821,0.0104621,0.002028147,0.00008613059,0.0001201394,0.0006235794,0.001377669,0.00164356,0.01371483,0.01296841],"study_design_scores_gemma":[0.9643856,0.01547484,0.001338426,0.001497271,0.0008457671,0.0000295289,0.00005119302,0.0007450235,0.0004876469,0.001072024,0.0140251,0.00004753184],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.006584058,0.0007278216,0.001081544,0.0005061371,0.0009773527,0.9852383,0.00305807,0.0001198401,0.001706842],"genre_scores_gemma":[0.005199132,0.0002630572,0.001411657,0.0004018616,0.0001132504,0.991457,0.0003549218,0.000008075556,0.0007910423],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.07496249,"threshold_uncertainty_score":0.2507746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02088207119201434,"score_gpt":0.3059280617605792,"score_spread":0.2850459905685648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}