{"id":"W4388902110","doi":"10.2196/preprints.48576","title":"Dobutamine and Goal-Directed Fluid Therapy for Improving Tissue Oxygenation in Deep Inferior Epigastric Perforator (DIEP) Flap Breast Reconstruction Surgery: Protocol for a Randomized Controlled Trial (Preprint)","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Reconstructive Surgery and Microvascular Techniques","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"DIEP flap; Medicine; Breast reconstruction; Perioperative; Surgery; Breast cancer; Randomized controlled trial; Oxygenation; Anesthesia; Cancer; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007416774,0.000797535,0.00500832,0.001483012,0.0001624126,0.0001653672,0.0001383561,0.0008882205,0.0001202086],"category_scores_gemma":[0.004445108,0.0006166311,0.001567526,0.0004008041,0.0002405226,0.0002182427,0.0001516326,0.0005697568,0.000002218365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000319538,"about_ca_system_score_gemma":0.0008958285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002454294,"about_ca_topic_score_gemma":0.00009074475,"domain_scores_codex":[0.9944494,0.0007465647,0.002530571,0.001374681,0.0003086344,0.0005901271],"domain_scores_gemma":[0.99369,0.003135508,0.001253349,0.0006051308,0.001135126,0.0001808874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7402505,0.0002131633,0.0006468252,0.00120456,0.0007408154,0.000004382837,0.00007391659,0.000005702264,0.01777549,0.00002840053,0.0000759571,0.2389804],"study_design_scores_gemma":[0.952449,0.0004902373,0.0009976424,0.0009129432,0.0003920369,0.0002397494,0.00008152459,0.01311881,0.02922487,0.001187177,0.0002417635,0.0006642813],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3547677,0.00008691819,0.03348542,0.000243662,0.0008390447,0.6096545,0.00007423139,0.0007976271,0.00005086834],"genre_scores_gemma":[0.04700364,0.0001930384,0.01970355,0.00004108154,0.0006455832,0.9315423,0.0003540293,0.0001551679,0.000361608],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.3218878,"threshold_uncertainty_score":0.9996285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02088207119201434,"score_gpt":0.3059280617605792,"score_spread":0.2850459905685648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}