{"id":"W4388902498","doi":"10.1038/s41581-023-00787-w","title":"Mechanisms and consequences of sex differences in immune responses","year":2023,"lang":"en","type":"review","venue":"Nature Reviews Nephrology","topic":"Sex and Gender in Healthcare","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"","keywords":"Immune system; Biology; Sexual characteristics; Testosterone (patch); Hormone; Sex characteristics; Sexual differentiation; Immunology; Physiology; Endocrinology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00117162,0.0008128618,0.002025438,0.00120077,0.0002336893,0.001311216,0.0008332239,0.001342397,0.003517306],"category_scores_gemma":[0.001637534,0.0002648505,0.0006442039,0.001397497,0.0007767373,0.001133822,0.001027141,0.001909445,0.000851893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007766326,"about_ca_system_score_gemma":0.001517422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001599454,"about_ca_topic_score_gemma":0.002540304,"domain_scores_codex":[0.999661,0.00008903937,0.00004242699,0.00006318168,0.0001004916,0.00004391493],"domain_scores_gemma":[0.9994795,0.0003111945,0.00006483633,0.00001225082,0.00009539882,0.00003679952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002497299,0.00004998701,0.0008288667,0.01821032,0.0002640976,0.0002041429,0.0001094427,0.0005071455,0.001240008,0.007388609,0.03101825,0.9399294],"study_design_scores_gemma":[0.00007448551,0.0001668483,0.005773967,0.009673662,0.0005197668,0.001339933,0.0002427985,0.0001691148,0.0004857524,0.01075662,0.9707446,0.0000524214],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008127787,0.9989668,0.00006095808,0.0003682376,0.0001834114,0.000002053423,0.00001819078,0.000002321659,0.0003167101],"genre_scores_gemma":[0.0005965219,0.9985317,0.00006600173,0.0002597766,0.0003016653,0.000005184284,0.00001905905,6.558147e-7,0.00021939],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003517306,"threshold_uncertainty_score":0.01176655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1682117463089869,"score_gpt":0.4364873770504308,"score_spread":0.2682756307414439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}