{"id":"W4388916284","doi":"10.1684/vir.2023.1021","title":"Gene therapy to cure HIV infection","year":2023,"lang":"en","type":"review","venue":"Virologie","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Genetic enhancement; Gene silencing; Human immunodeficiency virus (HIV); Gene; Medicine; Drug resistance; Immunology; Biology; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003186456,0.0006820568,0.0008305768,0.001611521,0.0002601348,0.0007123065,0.0004870481,0.0008253012,0.00337828],"category_scores_gemma":[0.0002847904,0.0002023242,0.0003829768,0.001014125,0.0004982677,0.0009173388,0.0004974597,0.001846476,0.002463599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005814075,"about_ca_system_score_gemma":0.0005423581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006935992,"about_ca_topic_score_gemma":0.001075045,"domain_scores_codex":[0.9998728,0.00002158,0.00001083082,0.00002319926,0.00005520494,0.0000163659],"domain_scores_gemma":[0.9999223,0.00003590925,0.000009905073,0.000004243118,0.0000194978,0.000008122314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004853218,0.0001029805,0.0001296853,0.009897067,0.00006174345,0.0002858331,0.0001053773,0.0005418576,0.01514918,0.01318621,0.0374302,0.9230614],"study_design_scores_gemma":[0.000008949697,0.00006948671,0.0002553945,0.00098711,0.00003024784,0.0009112622,0.00002901481,0.00008409617,0.002271856,0.002068851,0.9932728,0.00001085014],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002815258,0.9953617,0.0003905857,0.0002579593,0.0003521254,0.00000828876,0.00001863606,0.00001993923,0.003309218],"genre_scores_gemma":[0.001532682,0.9954603,0.0003324599,0.0002515565,0.0001174682,0.00001077839,0.00002782209,0.000003641842,0.002263113],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00337828,"threshold_uncertainty_score":0.01130146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1404525736264269,"score_gpt":0.4217606984372064,"score_spread":0.2813081248107794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}