{"id":"W4388948415","doi":"10.1016/j.ijrobp.2023.09.005","title":"A User's Guide and Summary of Pediatric Normal Tissue Effects in the Clinic (PENTEC): Radiation Dose-Volume Response for Adverse Effects After Childhood Cancer Therapy and Future Directions","year":2023,"lang":"en","type":"review","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Maryland Department of Health; U.S. Department of Defense; University of North Carolina at Chapel Hill; National Institutes of Health; Pediatric Oncology Group of Ontario; University of North Carolina Wilmington; University of Alabama; American Association of Physicists in Medicine; University of Miami; St. Jude Children's Research Hospital","keywords":"Adverse effect; Childhood cancer; Medicine; Radiation therapy; Cancer; Pediatric cancer; Oncology; Nuclear medicine; Medical physics; Intensive care medicine; Radiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001392933,0.001608427,0.002852144,0.006065106,0.0002555662,0.001388048,0.001962927,0.00141438,0.08068976],"category_scores_gemma":[0.004673289,0.00077808,0.002423635,0.005208256,0.0003218852,0.001356709,0.0009970303,0.001689781,0.03604494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007259899,"about_ca_system_score_gemma":0.002089149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006960212,"about_ca_topic_score_gemma":0.01576713,"domain_scores_codex":[0.9991934,0.0001838085,0.0002217849,0.00006514815,0.0002954321,0.00004048487],"domain_scores_gemma":[0.9963143,0.001915755,0.0005643035,0.00009729598,0.0009582232,0.0001500505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007809265,0.00005026404,0.0001495223,0.01884784,0.00008968424,0.00007609645,0.00004366299,0.0002357099,0.000547867,0.001008437,0.5454388,0.4334339],"study_design_scores_gemma":[0.00006658822,0.00008195062,0.001674084,0.009176073,0.0001200285,0.0007194034,0.00002806576,0.0001583699,0.0002040485,0.0007994401,0.986943,0.00002894857],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007372448,0.8916127,0.009384904,0.006712175,0.003901185,0.001789597,0.04492627,0.004055941,0.03688003],"genre_scores_gemma":[0.002726619,0.8448505,0.03678067,0.009225937,0.002200062,0.001988153,0.02284778,0.0008039373,0.0785763],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.08068976,"threshold_uncertainty_score":0.2699341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02839774747761829,"score_gpt":0.3964502399719996,"score_spread":0.3680524924943813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}