{"id":"W4388981162","doi":"10.1684/vir.2023.1024","title":"Gene therapy to cure HIV infection","year":2023,"lang":"en","type":"review","venue":"Virologie","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Genetic enhancement; Gene silencing; Human immunodeficiency virus (HIV); Gene; Medicine; Drug resistance; Immunology; Biology; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004661395,0.0004200253,0.0006930009,0.0002282308,0.00009333669,0.00003894245,0.0005219816,0.0007066168,0.0000711292],"category_scores_gemma":[0.000113062,0.0003366618,0.0004354999,0.0004469141,0.00006618857,0.000001721597,0.0002991522,0.0003409006,0.001756572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005403578,"about_ca_system_score_gemma":0.000319263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001138551,"about_ca_topic_score_gemma":0.00005291983,"domain_scores_codex":[0.997861,0.0003180183,0.0003378607,0.0007515418,0.0002113438,0.000520182],"domain_scores_gemma":[0.998731,0.00003817101,0.0001121083,0.0009149729,0.00006043589,0.0001433264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002386332,0.00005104235,0.000008010696,0.000523751,0.0003099991,0.00001393907,0.000005124328,0.00002515338,0.005742897,0.000001757066,0.01596144,0.9771183],"study_design_scores_gemma":[0.0001968369,0.002253554,0.000006881768,0.0001750529,0.00004064466,0.000009672185,8.341488e-7,9.453591e-7,0.005310409,0.00001765666,0.9916421,0.000345409],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002370343,0.9956983,0.00008648101,0.0001368523,0.0002993973,0.00102892,0.0001088899,0.0001089098,0.0001619412],"genre_scores_gemma":[0.00001985242,0.9953378,0.00007446751,0.0003292917,0.0008521806,0.0005001921,0.0006526459,0.0001396785,0.002093848],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9767728,"threshold_uncertainty_score":0.9999086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1404525736264269,"score_gpt":0.4217606984372064,"score_spread":0.2813081248107794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}