{"id":"W4389005275","doi":"10.1093/schbul/sbad164","title":"Disease Progression Patterns of Brain Morphology in Schizophrenia: More Progressed Stages in Treatment Resistance","year":2023,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science; Ontario Mental Health Foundation; Takeda Science Foundation; Canadian HIV Trials Network, Canadian Institutes of Health Research; Canadian Institutes of Health Research; Uehara Memorial Foundation; Watanabe Foundation","keywords":"Globus pallidus; Schizophrenia (object-oriented programming); Magnetic resonance imaging; Brain morphometry; Biomarker; Temporal lobe; Medicine; Neuroscience; Psychology; Internal medicine; Pathology; Basal ganglia; Biology; Epilepsy; Psychiatry; Radiology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000869042,0.0002821478,0.000285574,0.001280885,0.0002741309,0.000429223,0.0002193944,0.0003128824,0.001030817],"category_scores_gemma":[0.002045695,0.0001843506,0.0003560044,0.0006619826,0.0003844177,0.0003848499,0.0003955292,0.0004046612,0.0001253557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002784888,"about_ca_system_score_gemma":0.0002354697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00201861,"about_ca_topic_score_gemma":0.002640441,"domain_scores_codex":[0.999749,0.00008169592,0.00004168917,0.00006506917,0.00003839055,0.00002415959],"domain_scores_gemma":[0.9981039,0.0002486108,0.001207533,0.0001400273,0.0001546229,0.0001452405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003993515,0.00003466694,0.9909477,0.0000142756,0.00004314826,0.0001078832,0.0001547366,0.0002637765,0.003902194,0.0000346017,0.00002705939,0.004070614],"study_design_scores_gemma":[0.00000803137,0.0001034522,0.9985548,0.000003792738,0.00001546612,0.0002938814,0.00006723814,0.0005312965,0.0003073064,0.00007207734,0.00003872993,0.000004036705],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995905,0.00004928324,0.0001578171,0.00001176154,5.718139e-7,0.000008028183,0.00007288956,0.000003328887,0.0001057924],"genre_scores_gemma":[0.9994534,0.00002630817,0.0003372664,0.000004249023,0.000002200235,0.00000495581,0.0001323328,0.000002395609,0.00003710691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00201861,"threshold_uncertainty_score":0.004595935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01998166902051428,"score_gpt":0.3195718280074031,"score_spread":0.2995901589868888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}