{"id":"W4389008082","doi":"10.1096/fasebj.30.1_supplement.1107.3","title":"Synthetic Lethal Approaches to Metastatic Breast Cancer Therapy","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"Breast cancer; Metastatic breast cancer; Medicine; Cancer research; Metastasis; Cancer; Cancer cell; Angiogenesis; Cell; CA15-3; Oncology; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003837044,0.0007495414,0.0005121385,0.0006292102,0.0002757683,0.0004519357,0.0005686824,0.000527257,0.003096005],"category_scores_gemma":[0.0001842813,0.0002538046,0.0004455706,0.0002937706,0.0005222236,0.0002922096,0.000600705,0.00136873,0.0009312446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004694634,"about_ca_system_score_gemma":0.0002991947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003205546,"about_ca_topic_score_gemma":0.000433435,"domain_scores_codex":[0.9997275,0.0000605569,0.00001327802,0.0000450661,0.0001003851,0.00005323348],"domain_scores_gemma":[0.9998822,0.00002602102,0.00003115062,0.00001904952,0.00001974047,0.00002183015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001918647,0.0001809308,0.0002018545,0.0003908267,0.00003233133,0.0002605985,0.00005173009,0.0007700954,0.9760619,0.004221095,0.001461782,0.01617502],"study_design_scores_gemma":[0.0001286315,0.001797204,0.001251617,0.00007257894,0.00009547803,0.003244082,0.00006966593,0.003058792,0.8884421,0.001923325,0.09988555,0.00003093906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.582341,0.09076276,0.2664964,0.004471591,0.001399886,0.001732387,0.003857396,0.002667224,0.04627136],"genre_scores_gemma":[0.8862852,0.0381015,0.0508506,0.001223594,0.0001770366,0.001013688,0.003315281,0.0001911716,0.01884191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003096005,"threshold_uncertainty_score":0.0103572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05174708269192795,"score_gpt":0.2540313720905447,"score_spread":0.2022842893986167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}