{"id":"W4389008246","doi":"10.1096/fasebj.30.1_supplement.1197.6","title":"In Vivo Treatment with Natriuretic Peptide Receptor Type C Agonist Attenuates Overexpression of Cell Cycles Proteins and Hyperproliferation of Vascular Smooth Muscle Cells from SHR : Molecular Mechanisms","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemical Synthesis and Reactions","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Vascular smooth muscle; Endocrinology; Internal medicine; Atrial natriuretic peptide; Chemistry; Cell growth; Cyclin D1; Protein kinase B; In vivo; Phosphorylation; Cyclin E; Receptor; Agonist; Cell cycle; Biology; Medicine; Biochemistry; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001231359,0.0003569525,0.0003558753,0.0001875859,0.0001614925,0.0001211321,0.000132084,0.0002308701,0.001718835],"category_scores_gemma":[0.00007504484,0.0001799547,0.0002454338,0.00008019454,0.000181618,0.0001617952,0.000135849,0.0007928692,0.0002466374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001060529,"about_ca_system_score_gemma":0.000192244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005765862,"about_ca_topic_score_gemma":0.001196159,"domain_scores_codex":[0.9999148,0.00001555013,0.000007628085,0.00001224352,0.00001808684,0.00003172905],"domain_scores_gemma":[0.9998991,0.00001069937,0.00002631619,0.000009369789,0.000009688973,0.00004474367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004272274,0.000143227,0.0001600107,0.0000496933,0.00000680842,0.00005137459,0.00001506115,0.000020441,0.9980887,0.00001805956,0.00003577134,0.0009836336],"study_design_scores_gemma":[0.0001210938,0.005321182,0.02207615,0.00001596998,0.00006214607,0.0003558487,0.00007681111,0.000670683,0.9694467,0.00005957574,0.001784114,0.00000971295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974988,0.00115821,0.0004853334,0.00009076718,0.00003637849,0.00002203025,0.0001658617,0.00003436398,0.0005082389],"genre_scores_gemma":[0.9937561,0.001770903,0.0009621672,0.00008749364,0.00003530279,0.00008939074,0.000525593,0.00001053518,0.002762478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718835,"threshold_uncertainty_score":0.00575012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006667897408356022,"score_gpt":0.1968468387612813,"score_spread":0.1901789413529253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}