{"id":"W4389021195","doi":"10.1096/fasebj.31.1_supplement.718.2","title":"Neuronal nitric oxide synthase inhibits store‐operated Ca <sup>2+</sup> entry in cardiomyocytes via S‐nitrosylation of stromal interaction molecule‐1","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"STIM1; ORAI1; Chemistry; Cell biology; Nitric oxide; Nitrosylation; S-Nitrosylation; Endoplasmic reticulum; HEK 293 cells; Nitric oxide synthase; Biophysics; Biochemistry; Cysteine; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002827688,0.0003456057,0.000390108,0.00009462056,0.0001125035,0.0002008572,0.0002476308,0.0002214307,0.000753594],"category_scores_gemma":[0.0001472342,0.0001310808,0.000286309,0.00008198927,0.0002609521,0.0002001514,0.0001931157,0.0005552748,0.0002181426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002016446,"about_ca_system_score_gemma":0.000347698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006039664,"about_ca_topic_score_gemma":0.001406412,"domain_scores_codex":[0.9998415,0.00003423611,0.00002703631,0.00002211746,0.00003036838,0.00004471673],"domain_scores_gemma":[0.9999081,0.00002016973,0.00001803199,0.00001053758,0.000008809269,0.00003442921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003275136,0.00006335023,0.0001217,0.00006148013,0.00001031102,0.00003927965,0.00001408721,0.0000459336,0.9981498,0.00005842501,0.00005304485,0.001055217],"study_design_scores_gemma":[0.00007197045,0.0008275912,0.004055284,0.000008510748,0.0000246682,0.0001078077,0.00003246129,0.001430575,0.9922088,0.00003898736,0.001188455,0.000004747926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956282,0.001752046,0.001123603,0.0001375434,0.00006852059,0.00002420269,0.0001408306,0.00005452439,0.001070532],"genre_scores_gemma":[0.9940733,0.001674312,0.001761307,0.00009865206,0.00003374097,0.00007138862,0.0003459908,0.00001806785,0.001923222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000753594,"threshold_uncertainty_score":0.002520978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02518848655158488,"score_gpt":0.266095915878012,"score_spread":0.2409074293264271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}