{"id":"W4389021577","doi":"10.1096/fasebj.31.1_supplement.696.7","title":"Mitochondrial‐Targeted Peptide SBT‐20 Improves Mitochondrial Bioenergetics In Duchenne Muscular Dystrophy In a Mitochondrial Creatine Kinase Dependent Manner","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"James H. Cummings Foundation","keywords":"Duchenne muscular dystrophy; Dystrophin; Creatine kinase; Bioenergetics; Internal medicine; Mitochondrion; Endocrinology; Myopathy; Creatine; Oxidative phosphorylation; Utrophin; Muscular dystrophy; Mitochondrial myopathy; Biology; Cardiomyopathy; Chemistry; Mitochondrial DNA; Medicine; Biochemistry; Heart failure; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002179925,0.000627898,0.0007743864,0.0004185369,0.0001988772,0.0002719733,0.0004012,0.0006027641,0.001960013],"category_scores_gemma":[0.0001295745,0.0001927546,0.0002317171,0.0001596853,0.0003459835,0.000278704,0.0001761346,0.0007801448,0.0002485202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000236141,"about_ca_system_score_gemma":0.000259293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001007495,"about_ca_topic_score_gemma":0.001579973,"domain_scores_codex":[0.99986,0.00002647776,0.00002148193,0.00002795084,0.00002749704,0.00003655708],"domain_scores_gemma":[0.9998288,0.0000168855,0.00004240596,0.00001111106,0.0000185613,0.00008216448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001568002,0.0005334352,0.0001299396,0.0001015662,0.00001648616,0.00006692719,0.00001879279,0.00008178419,0.9953151,0.00002503774,0.0001019204,0.002040982],"study_design_scores_gemma":[0.0008796263,0.02147603,0.01145647,0.00004328501,0.0001332911,0.0003734297,0.00008596407,0.0009383476,0.9610862,0.00006664159,0.003438961,0.00002181041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971502,0.001067157,0.0005284089,0.0001101134,0.00005282497,0.00006143421,0.0003255255,0.0001342361,0.0005700643],"genre_scores_gemma":[0.9917557,0.001657497,0.001751235,0.00017394,0.00003218438,0.0001136919,0.0007033642,0.00003291119,0.00377947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001960013,"threshold_uncertainty_score":0.006556869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008702889694360316,"score_gpt":0.241389160885579,"score_spread":0.2326862711912187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}