{"id":"W4389024284","doi":"10.1096/fasebj.31.1_supplement.101.3","title":"To kill a bacterium, you need to think like a bacterium","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Bacteria; Biology; Gene; Chemically defined medium; Microbial metabolism; Amino acid; Bacterial growth; Biochemistry; Escherichia coli; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879385,0.001354493,0.0009134241,0.0007234036,0.0025002,0.004508493,0.0007840804,0.00492839,0.02351758],"category_scores_gemma":[0.003787756,0.0004312552,0.0008070939,0.0004153926,0.007632647,0.006058243,0.003156139,0.007033342,0.02731384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001036876,"about_ca_system_score_gemma":0.001743001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146242,"about_ca_topic_score_gemma":0.001901554,"domain_scores_codex":[0.9981096,0.0006964369,0.00008282291,0.0002159528,0.0006927003,0.0002024917],"domain_scores_gemma":[0.9979824,0.0005183286,0.0002016247,0.000192629,0.0005554149,0.0005495497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002094469,0.0002378506,0.002582186,0.002490159,0.00008217763,0.0007047058,0.004552692,0.0001935187,0.02449943,0.03215738,0.7303151,0.2019753],"study_design_scores_gemma":[0.00001383586,0.0001700293,0.0005397027,0.0004229764,0.00002063808,0.0009975554,0.002845226,0.00006005951,0.001580525,0.008623499,0.9846948,0.000031243],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01281147,0.121721,0.03159337,0.5868299,0.06836325,0.0004084954,0.0004584324,0.002464293,0.1753498],"genre_scores_gemma":[0.1124567,0.09909452,0.0638374,0.382226,0.01262295,0.0004804862,0.0006029984,0.00109416,0.3275848],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02351758,"threshold_uncertainty_score":0.07867414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09020165489462605,"score_gpt":0.4074106208349164,"score_spread":0.3172089659402904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}