{"id":"W4389027210","doi":"10.1096/fasebj.30.1_supplement.710.4","title":"Identification of potential PAR‐regulating proteinases in agricultural dust using an activity‐based serine proteinase probe","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute for Occupational Safety and Health","keywords":"Enzyme; Benzamidine; Trypsin; Serine; Biochemistry; Serine Proteinase Inhibitors; Proteinase 3; Chemistry; PMSF; Serine protease; Molecular biology; Biology; Inflammation; Protease; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003185579,0.0005679121,0.0003791528,0.0003639582,0.0001794463,0.0002534295,0.0003203716,0.0006456963,0.001764544],"category_scores_gemma":[0.0003322857,0.0001961245,0.0003824239,0.0002112944,0.0002324256,0.0003006576,0.0001814639,0.0007440162,0.0005055057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002148367,"about_ca_system_score_gemma":0.000149502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000350601,"about_ca_topic_score_gemma":0.0005202643,"domain_scores_codex":[0.9997901,0.00003921332,0.00001496451,0.0000625612,0.00004528719,0.00004776479],"domain_scores_gemma":[0.9997547,0.0001042044,0.00005532385,0.0000196132,0.0000331167,0.00003307015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005120787,0.00001041474,0.00009972241,0.00002846309,0.000003556304,0.00003020124,0.00000575203,0.00001398169,0.9991416,0.00002076376,0.00001144782,0.0005828368],"study_design_scores_gemma":[0.000016546,0.0003759845,0.006811687,0.00000433592,0.0000194503,0.0005579896,0.00002566099,0.0007625571,0.989754,0.00004750394,0.001619291,0.000004949638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521297,0.003140278,0.04174625,0.0003617312,0.00006309248,0.0001665175,0.0005285841,0.0001191459,0.001744596],"genre_scores_gemma":[0.9238783,0.002970802,0.06675146,0.0004323723,0.00006423626,0.0002010317,0.001417071,0.00004509851,0.004239594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001764544,"threshold_uncertainty_score":0.005902946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02786501375698032,"score_gpt":0.2738370470315495,"score_spread":0.2459720332745692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}