{"id":"W4389029637","doi":"10.1093/ofid/ofad500.2333","title":"2722. Risk of Infectious Adverse Events of Venetoclax Therapy in the Treatment of Hematologic Malignancies: A Systematic Review and Bayesian Meta-Analysis of Randomized Controlled Trials","year":2023,"lang":"en","type":"review","venue":"Open Forum Infectious Diseases","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; McGill University","funders":"","keywords":"Venetoclax; Medicine; Neutropenia; Internal medicine; Adverse effect; Randomized controlled trial; Febrile neutropenia; Regimen; Oncology; Leukemia; Chronic lymphocytic leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02373429,0.003114311,0.02005947,0.00957327,0.0005695291,0.003552508,0.002183092,0.002715491,0.004305177],"category_scores_gemma":[0.05777958,0.001988832,0.04876061,0.008055302,0.0008464541,0.0019742,0.00157357,0.002645231,0.0004636918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002609358,"about_ca_system_score_gemma":0.003115169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006345503,"about_ca_topic_score_gemma":0.00913323,"domain_scores_codex":[0.9744655,0.01510841,0.005733492,0.002027938,0.00230149,0.0003631076],"domain_scores_gemma":[0.9570996,0.03332447,0.006339407,0.000989164,0.001897732,0.0003496195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001527984,0.00001909606,0.002418075,0.2830769,0.7015505,0.00006491363,0.00004074482,0.0007726949,0.0001218989,0.0001665427,0.0004558822,0.009784644],"study_design_scores_gemma":[0.0006276229,0.0001465741,0.002325882,0.02266113,0.9720129,0.00007612001,0.0000201488,0.0004264324,0.00008033322,0.0003370665,0.001264609,0.00002122298],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003272311,0.9935325,0.001314223,0.0002323197,0.0001521776,0.0003840581,0.0007619541,0.00003661193,0.0003137131],"genre_scores_gemma":[0.2655292,0.7229193,0.005994211,0.001266353,0.0003776852,0.002055097,0.001363227,0.00006696878,0.0004279006],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02373429,"threshold_uncertainty_score":0.1255204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1076177235496019,"score_gpt":0.422199907288947,"score_spread":0.3145821837393452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}