{"id":"W4389038563","doi":"10.1002/pca.3309","title":"Integrating multi‐index determination coupled with hierarchical cluster analysis to evaluate the quality consistency of PVE30, an anti‐HSV “glycoprotein” macromolecule of Prunellae Spica","year":2023,"lang":"en","type":"article","venue":"Phytochemical Analysis","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"Special Project for Research and Development in Key areas of Guangdong Province; National Natural Science Foundation of China","keywords":"Chemistry; Monosaccharide; Chromatography; Glycoprotein; Macromolecule; Consistency (knowledge bases); Biochemistry; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002707902,0.0004010944,0.001311388,0.0007161016,0.0002422006,0.00003039119,0.0008147864,0.0003341905,0.000467101],"category_scores_gemma":[0.0009681109,0.0002557689,0.0007845106,0.007185509,0.0006660594,0.000118696,0.000307174,0.001023255,0.00001572007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008882484,"about_ca_system_score_gemma":0.0000818353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001799188,"about_ca_topic_score_gemma":0.0002702778,"domain_scores_codex":[0.995092,0.001713833,0.001108515,0.0007515757,0.0007497963,0.0005842775],"domain_scores_gemma":[0.9956854,0.002167042,0.0004918639,0.0005928739,0.0006944896,0.0003683141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001762489,0.0007599406,0.03110569,0.0001093166,0.007740405,0.00002392997,0.0005240316,0.02264395,0.9320481,0.00009737591,0.0000863005,0.003098457],"study_design_scores_gemma":[0.00166466,0.0003513497,0.05345446,0.00001558492,0.00952231,0.000002775969,0.000128152,0.6938987,0.2402831,0.0002693314,0.00004745855,0.0003621742],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884319,0.00005990676,0.008638647,0.001491327,0.00006252148,0.000926906,0.0001073917,0.0001056529,0.00017578],"genre_scores_gemma":[0.9965355,0.00001365058,0.001977726,0.0009471294,0.00006424911,0.0001673321,0.0001963734,0.0000213919,0.00007665791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6917651,"threshold_uncertainty_score":0.9999894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.100682211748728,"score_gpt":0.4719844791559506,"score_spread":0.3713022674072226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}