{"id":"W4389038563","doi":"10.1002/pca.3309","title":"Integrating multi‐index determination coupled with hierarchical cluster analysis to evaluate the quality consistency of PVE30, an anti‐HSV “glycoprotein” macromolecule of Prunellae Spica","year":2023,"lang":"en","type":"article","venue":"Phytochemical Analysis","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"Special Project for Research and Development in Key areas of Guangdong Province; National Natural Science Foundation of China","keywords":"Chemistry; Monosaccharide; Chromatography; Glycoprotein; Macromolecule; Consistency (knowledge bases); Biochemistry; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00220848,0.0008707312,0.0006384578,0.002410722,0.0004891635,0.0008469881,0.0005372093,0.0005207575,0.0004792883],"category_scores_gemma":[0.002448697,0.0003368451,0.0007208699,0.001540964,0.0006558792,0.0006001787,0.0007458129,0.0009924165,0.0003116968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005961549,"about_ca_system_score_gemma":0.0005755468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001969732,"about_ca_topic_score_gemma":0.002584722,"domain_scores_codex":[0.9980653,0.0002807109,0.000103099,0.000504136,0.0009356624,0.0001110226],"domain_scores_gemma":[0.9986786,0.0003159937,0.000257647,0.00009186106,0.0005859114,0.00007001563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004049678,0.0002144951,0.0140806,0.0004612008,0.0002322204,0.00009094636,0.0004372074,0.003515566,0.9086956,0.0005287724,0.0003786922,0.07095968],"study_design_scores_gemma":[0.00003945208,0.0007091266,0.06445627,0.00005045088,0.0002891675,0.0003995459,0.0003572631,0.1165007,0.8123533,0.001000407,0.003662352,0.000182129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6631867,0.004619695,0.3259186,0.0002235335,0.0001446038,0.0004696781,0.001030661,0.001204578,0.003201979],"genre_scores_gemma":[0.7618676,0.001294602,0.2341343,0.0001054107,0.00003613682,0.0004069589,0.0005943956,0.0001168155,0.001443743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002410722,"threshold_uncertainty_score":0.01167971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.100682211748728,"score_gpt":0.4719844791559506,"score_spread":0.3713022674072226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}