{"id":"W4389071712","doi":"","title":"Synthetic and External Controls in Clinical Trials – A Primer for Researchers","year":2020,"lang":"en","type":"article","venue":"SHILAP Revista de lepidopterología","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Primer (cosmetics); Clinical trial; Medicine; Psychology; Internal medicine; Chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.7710099,0.004219543,0.007643863,0.01442138,0.00279146,0.02241826,0.006947321,0.01186398,0.007831493],"category_scores_gemma":[0.8829522,0.002640158,0.007737665,0.01188083,0.02486998,0.01613129,0.009928495,0.02021496,0.001943853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01295391,"about_ca_system_score_gemma":0.02195581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001608249,"about_ca_topic_score_gemma":0.001353257,"domain_scores_codex":[0.1185117,0.7985467,0.05144877,0.006450874,0.02431811,0.0007239509],"domain_scores_gemma":[0.03581842,0.8809748,0.02819628,0.03166291,0.02220726,0.00114026],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002856807,0.000233712,0.002648247,0.07309666,0.005376761,0.0003216929,0.006744738,0.004733937,0.0006477585,0.3776456,0.05598477,0.4697094],"study_design_scores_gemma":[0.003029263,0.001762787,0.002019055,0.1359025,0.00331796,0.0006215246,0.002439127,0.01250871,0.002099071,0.5586638,0.2771733,0.0004629244],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.001619342,0.2150883,0.5933308,0.138335,0.02728088,0.01416817,0.001262087,0.0009113298,0.008004047],"genre_scores_gemma":[0.06234962,0.06153333,0.752305,0.03310224,0.01600599,0.07139293,0.0007043552,0.0005481379,0.002058389],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2289901,"threshold_uncertainty_score":0.2823856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1347420558095873,"score_gpt":0.4056129574685086,"score_spread":0.2708709016589214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}