{"id":"W4389076629","doi":"10.1093/gbe/evad216","title":"The Evolutionary Complexities of DNA Methylation in Animals: From Plasticity to Genetic Evolution","year":2023,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Epigenetics; DNA methylation; Phenotypic plasticity; Evolutionary biology; Genetics; Human evolutionary genetics; Genetic Fitness; Genome; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009336424,0.0002164627,0.0004843188,0.0004796919,0.00072376,0.001300127,0.0007620989,0.001162946,0.001031827],"category_scores_gemma":[0.00180548,0.0002603212,0.000337592,0.0004756022,0.003199945,0.0025515,0.001702128,0.001802464,0.0002542887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000750781,"about_ca_system_score_gemma":0.0005169139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046661,"about_ca_topic_score_gemma":0.00195363,"domain_scores_codex":[0.9995242,0.0001180448,0.00002716987,0.0001825694,0.00008915218,0.00005891233],"domain_scores_gemma":[0.9993188,0.0003121961,0.0001455296,0.00009763584,0.00006253785,0.00006326905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002902393,0.00004502554,0.05917686,0.001675726,0.0003843196,0.002042924,0.004748301,0.01134191,0.4487941,0.1858631,0.001939791,0.2836978],"study_design_scores_gemma":[0.00002247186,0.0005109888,0.1816336,0.0006947687,0.0003169662,0.004870937,0.002978904,0.01210365,0.06283339,0.5888801,0.1448517,0.0003025543],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6350818,0.128028,0.1797597,0.02675465,0.0007011229,0.00005588703,0.0006366165,0.0004212044,0.02856101],"genre_scores_gemma":[0.9518335,0.02400151,0.0188763,0.002199199,0.0003190863,0.00003256512,0.0001726071,0.00006514144,0.002500015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001300127,"threshold_uncertainty_score":0.005447328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791348077086444,"score_gpt":0.2689603294833233,"score_spread":0.2510468487124588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}