{"id":"W4389078506","doi":"10.21203/rs.3.rs-3651567/v1","title":"LNC01089-LINC00963/miR-1244-5p/IGF1 ceRNA axis might regulate FOXO signaling pathway in breast cancer patients: a biomarker discovery investigation","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"Breast cancer; Competing endogenous RNA; Biomarker; Biomarker discovery; Cancer research; Signal transduction; Cancer; Oncology; Medicine; Biology; Internal medicine; Cell biology; Gene; Proteomics; Genetics; RNA; Long non-coding RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004361294,0.0003565997,0.0005929673,0.000438385,0.0004524709,0.001094111,0.0003582484,0.0006904405,0.008982011],"category_scores_gemma":[0.0009223295,0.0002762548,0.0005652512,0.0005378762,0.0004218002,0.0003649321,0.0005781705,0.0008851211,0.001892648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000582151,"about_ca_system_score_gemma":0.0008750595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0021256,"about_ca_topic_score_gemma":0.003434916,"domain_scores_codex":[0.99968,0.00003175817,0.00001908829,0.0001074367,0.00009449852,0.00006720211],"domain_scores_gemma":[0.9997571,0.00004294987,0.00008207573,0.00002352922,0.00004031294,0.00005396469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0120181,0.0004928199,0.3087767,0.001516175,0.001370143,0.002698268,0.0005144201,0.001675691,0.4578637,0.006414467,0.02573719,0.1809223],"study_design_scores_gemma":[0.001633949,0.001615484,0.6176205,0.0003831623,0.003128672,0.005736309,0.0009576476,0.01569189,0.2084849,0.01339377,0.1311509,0.0002028012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9246915,0.0186789,0.01050446,0.004486446,0.00142416,0.0001530071,0.013077,0.001233674,0.0257508],"genre_scores_gemma":[0.9733743,0.002056606,0.004881506,0.001265193,0.0001700321,0.0001300084,0.005830765,0.0002798698,0.01201171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008982011,"threshold_uncertainty_score":0.03004777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04257837447512802,"score_gpt":0.3458420952237432,"score_spread":0.3032637207486151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}