{"id":"W4389092954","doi":"10.3389/fcvm.2023.1273596","title":"Role of vascular smooth muscle cell clonality in atherosclerosis","year":2023,"lang":"en","type":"review","venue":"Frontiers in Cardiovascular Medicine","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute","keywords":"Progenitor cell; Biology; Disease; Inflammation; Phenotype; Cell type; Stem cell; clone (Java method); Mural cell; Cell; Vascular smooth muscle; Smooth muscle; Immunology; Neuroscience; Pathology; Cell biology; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009131956,0.0002840125,0.0007258069,0.0006654569,0.0002902425,0.001017839,0.0004798307,0.0007424024,0.0007274987],"category_scores_gemma":[0.000470337,0.0001255063,0.0001849328,0.0005590183,0.0009601534,0.00103646,0.0005929976,0.001119978,0.000349661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005217101,"about_ca_system_score_gemma":0.0008332617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003199491,"about_ca_topic_score_gemma":0.000441193,"domain_scores_codex":[0.9997707,0.00004817811,0.00002686236,0.00005643723,0.00007104413,0.00002689791],"domain_scores_gemma":[0.9997434,0.0001088981,0.00004253242,0.00001125311,0.00006128905,0.00003268309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002777947,0.00007310652,0.001857777,0.01151783,0.00007662046,0.001304173,0.0006791108,0.0007802069,0.0669826,0.06020862,0.01086431,0.8453779],"study_design_scores_gemma":[0.00002682266,0.0005773108,0.007580582,0.002191532,0.000179244,0.003800893,0.0005043317,0.000862688,0.02561534,0.02516901,0.9334206,0.000071705],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002969523,0.9925253,0.001520352,0.0009622269,0.0003837966,0.000005910797,0.00001839808,0.00001391072,0.001600554],"genre_scores_gemma":[0.02205126,0.9743312,0.001284388,0.000409593,0.0008678914,0.00001916224,0.00003549781,0.000004886381,0.000996084],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001017839,"threshold_uncertainty_score":0.004829526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02848171270247368,"score_gpt":0.2586940838263745,"score_spread":0.2302123711239008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}