{"id":"W4389098299","doi":"10.3389/fimmu.2023.1269614","title":"Killer instincts: natural killer cells as multifactorial cancer immunotherapy","year":2023,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Dalhousie University","keywords":"Immunotherapy; Receptor; Biology; Cancer immunotherapy; Immunology; Natural killer cell; Cancer cell; Cancer research; Cancer; Immune system; Cytotoxic T cell; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000493411,0.0008846662,0.001086981,0.001392792,0.0002529964,0.001207093,0.0009594341,0.00126689,0.003320357],"category_scores_gemma":[0.0003863839,0.0002262611,0.0003797808,0.001316632,0.0007340634,0.001852098,0.000817775,0.002571146,0.002643886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007979817,"about_ca_system_score_gemma":0.0008088062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004811172,"about_ca_topic_score_gemma":0.0008104217,"domain_scores_codex":[0.9998522,0.00003002489,0.00001371262,0.00002293385,0.00005952594,0.00002164242],"domain_scores_gemma":[0.999843,0.00007308863,0.00001800648,0.000006187463,0.00003831409,0.00002145613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007973638,0.00008023914,0.0001154152,0.01179076,0.00006696947,0.0001957302,0.0000897787,0.0005209311,0.003258268,0.01986713,0.03983109,0.9241039],"study_design_scores_gemma":[0.00001024915,0.00006021242,0.000233922,0.001470924,0.00002743774,0.0005253662,0.0000369018,0.0000725885,0.0003686293,0.004503034,0.9926803,0.00001031531],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001039738,0.9972376,0.0002501404,0.0003467674,0.0005080067,0.000004546912,0.000008266358,0.000009946059,0.001530737],"genre_scores_gemma":[0.0009728912,0.9967967,0.0002024564,0.0003252174,0.0003623173,0.000007251105,0.00002114679,0.000002120153,0.001309886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003320357,"threshold_uncertainty_score":0.01110774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02153517916472178,"score_gpt":0.296696184081089,"score_spread":0.2751610049163672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}