{"id":"W4389117307","doi":"10.1016/j.prp.2023.154988","title":"EZH2 as a potential therapeutic target for gastrointestinal cancers","year":2023,"lang":"en","type":"article","venue":"Pathology - Research and Practice","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"EZH2; microRNA; Cancer research; Cancer; Pancreatic cancer; Esophageal cancer; Biology; Colorectal cancer; Epigenetics; Medicine; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002525782,0.0001830657,0.0002822283,0.0002413243,0.0001251647,0.0004402396,0.0002175712,0.0003844632,0.00329809],"category_scores_gemma":[0.0002117226,0.00006987104,0.0001457818,0.0002267751,0.0001788336,0.0003028983,0.0002553901,0.0005529671,0.0005633332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002535895,"about_ca_system_score_gemma":0.0002128228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001593452,"about_ca_topic_score_gemma":0.0005133178,"domain_scores_codex":[0.9999427,0.00001429609,0.000003445929,0.00001113399,0.00001626174,0.00001220781],"domain_scores_gemma":[0.9999533,0.00001438974,0.00000911362,0.000003261474,0.000008225416,0.00001177417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002418895,0.0002738241,0.008822598,0.001847283,0.0002082218,0.002355401,0.000136665,0.001201775,0.248755,0.0107819,0.01519215,0.7080063],"study_design_scores_gemma":[0.0008105298,0.003434296,0.03394298,0.0004378118,0.0006224631,0.009410318,0.0004155235,0.003978318,0.2411296,0.01131759,0.694448,0.00005266043],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2524454,0.6829562,0.01081715,0.02064232,0.00135609,0.00008658093,0.0005211096,0.0003942818,0.0307809],"genre_scores_gemma":[0.8271568,0.1487894,0.005081289,0.002138877,0.0009553065,0.00006190498,0.0004504098,0.00003277859,0.01533325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00329809,"threshold_uncertainty_score":0.01103324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08226397314724165,"score_gpt":0.4355064957558167,"score_spread":0.3532425226085751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}