{"id":"W4389147357","doi":"10.1002/advs.202306463","title":"Long‐Acting Ocular Injectables: Are We Looking In The Right Direction?","year":2023,"lang":"en","type":"review","venue":"Advanced Science","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Krembil Foundation","keywords":"Drug delivery; Medicine; Drug; Bioavailability; Targeted drug delivery; Pharmacology; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005695965,0.0005981363,0.0008369947,0.001165598,0.0002003293,0.0009615371,0.0006018052,0.000950471,0.003402996],"category_scores_gemma":[0.0005445628,0.0002329681,0.0004313641,0.0009956197,0.0003879786,0.001665431,0.0003749922,0.001872164,0.001955504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000439563,"about_ca_system_score_gemma":0.0007972752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007625032,"about_ca_topic_score_gemma":0.001527483,"domain_scores_codex":[0.9998631,0.00002218389,0.00001543053,0.0000193367,0.00006193783,0.00001797173],"domain_scores_gemma":[0.9997661,0.0001178436,0.00003999889,0.000005746856,0.00005067147,0.0000196367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006368074,0.00006686489,0.0001269408,0.01185366,0.00004111404,0.0002313078,0.00007111948,0.0002410188,0.005095955,0.006098385,0.01949927,0.9566106],"study_design_scores_gemma":[0.00001755246,0.0001532281,0.0004322634,0.002565139,0.00005843219,0.001349424,0.00007818972,0.00009992591,0.001944437,0.001837822,0.9914414,0.00002223138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002064031,0.9978023,0.000251605,0.0003887499,0.0002183461,0.000004975374,0.00001438982,0.000009596331,0.00110357],"genre_scores_gemma":[0.001068034,0.997099,0.0003414723,0.0003015047,0.0001292694,0.000009048698,0.0000236634,0.000002735139,0.001025211],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003402996,"threshold_uncertainty_score":0.01138419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03556971932029991,"score_gpt":0.351676207980247,"score_spread":0.3161064886599471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}