{"id":"W4389147357","doi":"10.1002/advs.202306463","title":"Long‐Acting Ocular Injectables: Are We Looking In The Right Direction?","year":2023,"lang":"en","type":"review","venue":"Advanced Science","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Krembil Foundation","keywords":"Drug delivery; Medicine; Drug; Bioavailability; Targeted drug delivery; Pharmacology; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007809379,0.0002730094,0.0004411974,0.0002027542,0.000287994,0.0001077057,0.00109229,0.0001493071,0.000005908091],"category_scores_gemma":[0.0002854214,0.0001843235,0.0001901483,0.001262277,0.0002298459,0.00002279158,0.0002355734,0.0003003389,0.00004943224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006175899,"about_ca_system_score_gemma":0.000279415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001440837,"about_ca_topic_score_gemma":0.0001686205,"domain_scores_codex":[0.998019,0.0001089033,0.0003579533,0.0007535133,0.0003108665,0.0004498032],"domain_scores_gemma":[0.9988976,0.0000679421,0.0002766229,0.0006239599,0.00008472185,0.00004913552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006359728,0.00004203207,0.0000729455,0.001621378,0.00004020744,0.0000861509,0.0001528042,0.0002282985,0.001600372,0.00003545941,0.0002852966,0.9958287],"study_design_scores_gemma":[0.00008505043,0.00007637778,0.00003229338,0.005824362,0.00005037127,0.00006147746,0.0003342284,0.00001509671,0.001146024,0.00006775479,0.9919243,0.000382695],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009780232,0.9967271,0.0002951976,0.00003354,0.000506796,0.0003860415,0.00001029886,0.00002278018,0.00104021],"genre_scores_gemma":[0.002447435,0.9963725,0.00009706358,0.00008187912,0.0001735876,0.0001032473,0.00002493884,0.00002570873,0.0006736381],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.995446,"threshold_uncertainty_score":0.7516495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03556971932029991,"score_gpt":0.351676207980247,"score_spread":0.3161064886599471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}