{"id":"W4389164949","doi":"10.1038/s41467-023-43777-z","title":"Endogenous noise of neocortical neurons correlates with atypical sensory response variability in the Fmr1−/y mouse model of autism","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Coastal Health","funders":"Fondation de France; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Neuroscience; Autism; Sensory system; Sensory processing; Stimulus (psychology); Fragile X syndrome; Endogeny; Biological neural network; Psychology; Biology; Developmental psychology; Cognitive psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008893039,0.0001052187,0.0001639905,0.0001248497,0.0001633912,0.0000126293,0.000915903,0.0001617516,0.000002893976],"category_scores_gemma":[0.00274825,0.00007288157,0.0000620735,0.0008431349,0.0004653159,0.00007482282,0.0002038468,0.001050536,0.000005259893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002555721,"about_ca_system_score_gemma":0.00009627677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000133384,"about_ca_topic_score_gemma":0.00006049341,"domain_scores_codex":[0.9977031,0.001333169,0.0003019296,0.0002234923,0.0002613105,0.0001770092],"domain_scores_gemma":[0.9924393,0.005687435,0.0001123951,0.001666104,0.00005774786,0.00003699791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006670365,0.000411551,0.002339499,0.00001175834,0.000004139284,0.000004708466,0.000616953,0.008882977,0.912861,0.07395204,0.0001189862,0.0001292777],"study_design_scores_gemma":[0.0006900229,0.0003001923,0.08321345,0.00002910955,0.00004958189,0.00005767221,0.0001337015,0.8783579,0.03030704,0.006306002,0.000340877,0.0002144338],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904373,0.00002219044,0.0001660579,0.008207599,0.00004205192,0.0003929436,0.0001175327,0.00006025948,0.0005540565],"genre_scores_gemma":[0.9989945,0.00009954071,0.0002858322,0.0003965067,0.00000353302,0.00002419351,0.00001191802,0.00001325387,0.0001707581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8825541,"threshold_uncertainty_score":0.4564115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06183769202231353,"score_gpt":0.2901503723644788,"score_spread":0.2283126803421652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}