{"id":"W4389189910","doi":"10.1016/j.ccell.2023.11.002","title":"A road map for the treatment of pediatric diffuse midline glioma","year":2023,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; CHILDREN with CANCER UK; Brain Tumour Charity; Rosetrees Trust; Brain Research UK; National Cancer Institute; National Institutes of Health; Cancer Research UK; U.S. Department of Defense","keywords":"Clinical trial; Medicine; Transparency (behavior); Data sharing; Bioinformatics; Neuroscience; Pathology; Computer science; Psychology; Biology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003121818,0.001077474,0.0009277512,0.002962274,0.001817846,0.004489258,0.001771282,0.004364648,0.02635231],"category_scores_gemma":[0.006007552,0.0003746647,0.001567776,0.001192894,0.001554175,0.006149368,0.002775948,0.008306542,0.008035442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003422289,"about_ca_system_score_gemma":0.01443514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006021041,"about_ca_topic_score_gemma":0.0140988,"domain_scores_codex":[0.998285,0.000540432,0.0001952617,0.0001437534,0.0004541702,0.0003813643],"domain_scores_gemma":[0.9943522,0.001541841,0.0005053062,0.0001575692,0.001827768,0.001615177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006689155,0.000528764,0.002987792,0.001704675,0.0001183014,0.002655312,0.000192483,0.004665231,0.00143135,0.04933944,0.3064946,0.6292132],"study_design_scores_gemma":[0.0002492947,0.001519395,0.005687805,0.003721631,0.0002382188,0.004188816,0.001464367,0.003979809,0.001322324,0.08707738,0.8904117,0.0001392089],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.01237526,0.3168556,0.04932638,0.4930763,0.02160597,0.0006055419,0.002111975,0.002118848,0.1019241],"genre_scores_gemma":[0.1788503,0.5408497,0.1023379,0.0963432,0.02401666,0.001401992,0.005499366,0.000868299,0.04983264],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02635231,"threshold_uncertainty_score":0.0881573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03535538935155938,"score_gpt":0.3092539999478242,"score_spread":0.2738986105962647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}