{"id":"W4389195431","doi":"10.1016/j.autrev.2023.103485","title":"Invariant natural killer T cells in autoimmune cholangiopathies: Mechanistic insights and therapeutic implications","year":2023,"lang":"en","type":"review","venue":"Autoimmunity Reviews","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Faculty of Medicine, Dalhousie University; Canadian Institutes of Health Research; Dalhousie University","keywords":"CD1D; Autoimmunity; Natural killer T cell; Biology; Immunology; Immune system; Primary sclerosing cholangitis; Acquired immune system; Innate immune system; T cell; Medicine; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007298893,0.0009267671,0.00138787,0.001123934,0.0001682802,0.001115132,0.0008339905,0.00120532,0.002666768],"category_scores_gemma":[0.0006284754,0.000199816,0.0003138497,0.001232374,0.0005470156,0.00115249,0.0007352182,0.002177703,0.001734507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00053748,"about_ca_system_score_gemma":0.0008753109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005674295,"about_ca_topic_score_gemma":0.001243364,"domain_scores_codex":[0.9998485,0.00002594489,0.00001695499,0.00002466036,0.00006032459,0.00002365134],"domain_scores_gemma":[0.9997234,0.0001182576,0.00003676755,0.00000764179,0.00007114375,0.00004276993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001701026,0.0000592269,0.0001438301,0.007626412,0.00006318949,0.0002097939,0.00003140496,0.0004501967,0.003420962,0.004200469,0.04551293,0.9381114],"study_design_scores_gemma":[0.00004580117,0.00009053227,0.0006070767,0.00204261,0.00008983322,0.0009313832,0.00004611288,0.00009513531,0.0004756262,0.002471147,0.9930877,0.00001703411],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006769951,0.9988419,0.0001003113,0.0002802315,0.0002731876,0.000001635182,0.000009703386,0.000005056033,0.0004201983],"genre_scores_gemma":[0.0005443662,0.9981892,0.0001292823,0.0002323731,0.0003760408,0.000003506505,0.00002069784,0.000001040357,0.0005034864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002666768,"threshold_uncertainty_score":0.008921266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07149611978413702,"score_gpt":0.3198758131260232,"score_spread":0.2483796933418862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}