{"id":"W4389207861","doi":"10.1111/epi.17841","title":"Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?","year":2023,"lang":"en","type":"review","venue":"Epilepsia","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary","keywords":"Neuroimaging; Neuroscience; Drug development; Animal model; Epilepsy; Vigabatrin; Encephalopathy; Clinical trial; Bioinformatics; Medicine; Psychology; Drug; Biology; Anticonvulsant; Psychiatry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001033731,0.0009845021,0.001969676,0.001418509,0.0002014818,0.001246755,0.001261209,0.001519876,0.001746567],"category_scores_gemma":[0.0009124454,0.0002712575,0.000640947,0.001016597,0.0007544269,0.002198572,0.0005485691,0.002339526,0.001123336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005222509,"about_ca_system_score_gemma":0.001175147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084909,"about_ca_topic_score_gemma":0.001749896,"domain_scores_codex":[0.9998198,0.00004791261,0.00003476252,0.00002718835,0.00005125989,0.00001909281],"domain_scores_gemma":[0.9995573,0.0002605817,0.00004810292,0.00001730383,0.0000863504,0.00003020176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002251786,0.000155924,0.0003372218,0.04261634,0.0002663027,0.0007135821,0.0001353189,0.0004765939,0.004918803,0.008761191,0.02626407,0.9151294],"study_design_scores_gemma":[0.00008099813,0.0003895437,0.001567852,0.01188855,0.0004622841,0.00386952,0.0002168373,0.0002058071,0.001415782,0.007667345,0.9721733,0.0000621389],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001178169,0.9988398,0.00009219845,0.000438731,0.00009554437,0.000003061484,0.00001457418,0.000004970255,0.0003933437],"genre_scores_gemma":[0.0004211653,0.9990964,0.0001279294,0.0001711527,0.00006940735,0.000005108963,0.00001778026,8.289333e-7,0.00009029672],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001969676,"threshold_uncertainty_score":0.005842865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1451678394222382,"score_gpt":0.3754849792722155,"score_spread":0.2303171398499773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}