{"id":"W4389218826","doi":"10.1182/blood-2023-173873","title":"Improved Overall Survival with Axicabtagene Ciloleucel Vs Standard of Care in Second-Line Large B-Cell Lymphoma Among the Elderly: A Subgroup Analysis of ZUMA-7","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Hazard ratio; Internal medicine; Subgroup analysis; Oncology; Chemoimmunotherapy; Aggressive lymphoma; Intention-to-treat analysis; Lymphoma; Randomized controlled trial; Surgery; Confidence interval; Rituximab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001554588,0.0005760106,0.001604206,0.0005982245,0.0002403915,0.0009287639,0.0003797504,0.0005599801,0.001571654],"category_scores_gemma":[0.001468315,0.0001875961,0.004197519,0.0005637285,0.0002347967,0.0004832828,0.0004545306,0.0007504334,0.0002488175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004415073,"about_ca_system_score_gemma":0.0005075741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000657513,"about_ca_topic_score_gemma":0.002021991,"domain_scores_codex":[0.9993858,0.0002138251,0.00008807024,0.0001219155,0.00008675976,0.0001036139],"domain_scores_gemma":[0.9993325,0.0001978265,0.0001868728,0.00008610923,0.00005577941,0.0001408457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3942699,0.002261417,0.4722065,0.001597241,0.03238131,0.0006532452,0.0002719743,0.001244113,0.01074253,0.0002329839,0.003236552,0.08090235],"study_design_scores_gemma":[0.04604959,0.05247543,0.8541902,0.0003275185,0.03224759,0.001267932,0.0005763649,0.003911729,0.002210021,0.0008474613,0.0057939,0.0001023242],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943242,0.003999296,0.0001419207,0.0001496678,0.00005446186,0.0001317501,0.0006706936,0.000009591678,0.0005185102],"genre_scores_gemma":[0.9972778,0.0007653356,0.0001544543,0.0002280539,0.00009286647,0.0001575571,0.00107925,0.000005972326,0.0002387824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001604206,"threshold_uncertainty_score":0.008221567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250162557583315,"score_gpt":0.2699300756294732,"score_spread":0.25742845005364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}