{"id":"W4389227659","doi":"10.1158/2326-6074.tumimm23-a041","title":"Abstract A041: Rejuvenation: Innovative technology to improve T-cell antitumor properties through partial reprogramming","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reprogramming; Induced pluripotent stem cell; Epigenetics; Biology; Cell potency; Immunotherapy; Embryonic stem cell; T cell; Cytotoxic T cell; Stem cell; Cell therapy; Cell; Phenotype; Cancer research; Immunology; Cell biology; Immune system; Genetics; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002423208,0.0003512025,0.0002834485,0.0002875956,0.0001696947,0.0005076879,0.0003513827,0.0005000968,0.003407085],"category_scores_gemma":[0.0001555334,0.0001467833,0.0004329077,0.0002060208,0.0002118139,0.0003553754,0.0003357614,0.0008642911,0.001165552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001749776,"about_ca_system_score_gemma":0.0001747137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001770994,"about_ca_topic_score_gemma":0.0001412781,"domain_scores_codex":[0.9998373,0.00001743553,0.00001402603,0.00004610882,0.0000569426,0.00002806283],"domain_scores_gemma":[0.9998922,0.00001635244,0.00002938396,0.0000180262,0.0000234273,0.00002046735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006361006,0.0000281112,0.0001050157,0.0001078181,0.000008016904,0.00006502327,0.00002686096,0.0002677317,0.9853126,0.0005309246,0.000297609,0.01318669],"study_design_scores_gemma":[0.000009632079,0.0002822091,0.0005703108,0.00001282975,0.00003023886,0.000327867,0.00001225583,0.0008821454,0.9841284,0.0002131429,0.01352246,0.00000843701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8406524,0.01717689,0.1174026,0.0009019093,0.0007828507,0.0002619762,0.001737175,0.001704732,0.01937952],"genre_scores_gemma":[0.9506614,0.006039686,0.02502457,0.0004839431,0.0001301997,0.000161161,0.001034483,0.0002791581,0.01618534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003407085,"threshold_uncertainty_score":0.01139784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06679651810333476,"score_gpt":0.3892451637049841,"score_spread":0.3224486456016494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}