{"id":"W4389227694","doi":"10.1158/2326-6074.tumimm23-b025","title":"Abstract B025: Neutrophil depletion enhances the anti-tumor activity of CAR-T cells in an autochthonous model of non-small cell lung cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; T cell; CD8; Immunotherapy; Medicine; Infiltration (HVAC); Cell; Lung cancer; Cancer immunotherapy; Immune system; Immunology; Pathology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003492466,0.0004791341,0.0005415161,0.0003614045,0.0001588657,0.0003542933,0.000427693,0.0005448664,0.002765721],"category_scores_gemma":[0.0001259079,0.0002006645,0.0003652293,0.0001699485,0.0002822627,0.0002690199,0.000202738,0.001468236,0.0006838611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003562103,"about_ca_system_score_gemma":0.0003823221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001591235,"about_ca_topic_score_gemma":0.00188586,"domain_scores_codex":[0.9996055,0.00007974003,0.00003293759,0.00007352346,0.00009636553,0.0001119805],"domain_scores_gemma":[0.9997706,0.00004353451,0.00004616205,0.00003356709,0.00001921255,0.00008701195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007749476,0.0007333409,0.0001076073,0.0000680994,0.000008531291,0.00007883886,0.00002436154,0.0002140901,0.9954807,0.0001618681,0.000202271,0.002145351],"study_design_scores_gemma":[0.0002069881,0.006574737,0.002252384,0.00001110899,0.00001933558,0.0002150077,0.00002711044,0.002664407,0.9863881,0.00004514704,0.001588505,0.000007117717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954858,0.00078935,0.001172486,0.0001248023,0.0000615081,0.00009734106,0.0006148716,0.0001374726,0.001516396],"genre_scores_gemma":[0.9935613,0.0003838471,0.001262172,0.00007962942,0.0000214686,0.0001192883,0.0007275876,0.00003305703,0.003811861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002765721,"threshold_uncertainty_score":0.00925225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08007744742955278,"score_gpt":0.4022435364212251,"score_spread":0.3221660889916723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}