{"id":"W4389227750","doi":"10.1158/2326-6074.tumimm23-b034","title":"Abstract B034: CD27 is a new promising T cell co-stimulatory target for cancer immunotherapy","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer immunotherapy; Monoclonal antibody; T cell; Immunotherapy; CD8; Immunology; Cancer research; Immune system; Biology; Tumor necrosis factor alpha; Antibody; Cell biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008254036,0.0003575986,0.0001727146,0.0002695251,0.0001316701,0.000248552,0.0002408472,0.0002737365,0.005839175],"category_scores_gemma":[0.00005442517,0.00007929933,0.0001936126,0.000186649,0.00008124569,0.0001078764,0.0001475828,0.0003874185,0.002103744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175578,"about_ca_system_score_gemma":0.0002974447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005079742,"about_ca_topic_score_gemma":0.0005496651,"domain_scores_codex":[0.9999523,0.000007718844,0.000002353039,0.000008138438,0.0000123278,0.000017218],"domain_scores_gemma":[0.9999685,0.000002884429,0.000003882882,0.000001756655,0.000007796496,0.00001517553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000306566,0.0001106495,0.0004292185,0.0001049047,0.00001175695,0.00009502144,0.00000735002,0.0003308217,0.9817408,0.0002709939,0.001611837,0.0149802],"study_design_scores_gemma":[0.000115653,0.001509678,0.003747123,0.00002621357,0.00005385543,0.0007833659,0.00001907924,0.001459188,0.9387041,0.0002283132,0.05334419,0.000009143718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466918,0.0206647,0.009896659,0.0009328963,0.0002022426,0.0002431636,0.001876865,0.0003370828,0.01915457],"genre_scores_gemma":[0.9501525,0.007681422,0.009418825,0.0004943978,0.0001073803,0.0001790855,0.004936038,0.00007588384,0.02695449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005839175,"threshold_uncertainty_score":0.01953399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09209846402742795,"score_gpt":0.4146756453279528,"score_spread":0.3225771813005249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}