{"id":"W4389227754","doi":"10.1158/2326-6074.tumimm23-b001","title":"Abstract B001: Harnessing invariant natural killer T cell cytotoxicity for cancer therapy","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Cytotoxic T cell; Biology; Natural killer T cell; Immunology; Adoptive cell transfer; Cancer research; Population; Interleukin 21; Lymphokine-activated killer cell; Antigen; T cell; CD8; Immune system; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001122473,0.000264924,0.000382832,0.0005592722,0.001046953,0.00006948409,0.0005029074,0.000512142,0.005773801],"category_scores_gemma":[0.0001601743,0.0002287089,0.0001850948,0.0007085461,0.0005657823,0.0002635454,0.0001764152,0.001570273,0.001899389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003477066,"about_ca_system_score_gemma":0.000446426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442121,"about_ca_topic_score_gemma":0.0001145485,"domain_scores_codex":[0.9973043,0.0003941543,0.0004130228,0.0006063926,0.000103516,0.001178596],"domain_scores_gemma":[0.998196,0.0006793424,0.0001425901,0.0004586325,0.0004932306,0.00003022138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001483275,0.0001048214,0.0005465929,0.00003646936,0.0002951455,0.000004565365,0.0005293036,0.00002038401,0.8613808,0.0001464387,0.1223844,0.0130678],"study_design_scores_gemma":[0.002678869,0.0001971394,0.02713276,0.00007217957,0.00001105911,0.00001126249,0.0007258288,0.00005576259,0.5321507,0.000114287,0.4365792,0.0002709746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9234653,0.04654229,0.00003983458,0.004233022,0.02160623,0.001230152,0.00003299325,0.0003517002,0.002498467],"genre_scores_gemma":[0.888607,0.009924491,0.00001006881,0.0003481294,0.0002087978,0.001334956,0.00025273,0.00005805868,0.09925572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3292301,"threshold_uncertainty_score":0.9988778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09172463458641776,"score_gpt":0.3831439119877658,"score_spread":0.291419277401348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}