{"id":"W4389227754","doi":"10.1158/2326-6074.tumimm23-b001","title":"Abstract B001: Harnessing invariant natural killer T cell cytotoxicity for cancer therapy","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Cytotoxic T cell; Biology; Natural killer T cell; Immunology; Adoptive cell transfer; Cancer research; Population; Interleukin 21; Lymphokine-activated killer cell; Antigen; T cell; CD8; Immune system; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001391438,0.000326052,0.0002329528,0.0003426679,0.0000871973,0.0003970668,0.000161553,0.0002841021,0.003295508],"category_scores_gemma":[0.0001047395,0.00006214999,0.0002121142,0.0002302802,0.0001817545,0.0001851016,0.0002170449,0.0005933308,0.001101859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001782286,"about_ca_system_score_gemma":0.0002164683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001576243,"about_ca_topic_score_gemma":0.0001257938,"domain_scores_codex":[0.9998976,0.00001542618,0.000006506825,0.0000203781,0.00003715039,0.00002285458],"domain_scores_gemma":[0.9999607,0.000006689396,0.00001002218,0.000003676858,0.000007658562,0.0000113221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002109011,0.00008661556,0.0003252791,0.0001819878,0.000008518309,0.00004905124,0.000009629357,0.0001730746,0.9781341,0.0002491693,0.0005506799,0.02002099],"study_design_scores_gemma":[0.00008963692,0.001204995,0.003743321,0.0000378099,0.00004908388,0.0005373991,0.00002569057,0.002233879,0.9697751,0.0005492131,0.02174195,0.00001198583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9133518,0.02252415,0.04590117,0.00104546,0.0005524924,0.0003565778,0.002644785,0.001016069,0.01260756],"genre_scores_gemma":[0.9637235,0.006133866,0.01666548,0.0005480876,0.0001338766,0.0002034189,0.002387687,0.0001073182,0.01009674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003295508,"threshold_uncertainty_score":0.01102459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09172463458641776,"score_gpt":0.3831439119877658,"score_spread":0.291419277401348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}