{"id":"W4389227791","doi":"10.1158/2326-6074.tumimm23-pr03","title":"Abstract PR03: Hypoxia promotes inflammatory fibroblast formation in pancreatic cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tumor microenvironment; Stromal cell; Pancreatic cancer; Cancer research; Hypoxia (environmental); Cancer-Associated Fibroblasts; Immune system; Chemokine; Cancer cell; Stroma; Immunotherapy; Biology; Cancer immunotherapy; Cancer; Medicine; Immunology; Chemistry; Internal medicine; Immunohistochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001521831,0.0001820358,0.0001833328,0.00027678,0.0002712746,0.0004020747,0.0001609564,0.000293782,0.006241818],"category_scores_gemma":[0.0001219136,0.0001097032,0.000202366,0.0002524362,0.0001501482,0.0001961606,0.0002739295,0.0004190702,0.001155431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415541,"about_ca_system_score_gemma":0.0002473137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005678875,"about_ca_topic_score_gemma":0.0007122176,"domain_scores_codex":[0.9998809,0.00001687624,0.00001109489,0.00002687772,0.00003397423,0.00003026584],"domain_scores_gemma":[0.9999044,0.00001517155,0.00002107631,0.000008132851,0.00001506747,0.00003615357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006775479,0.00008877558,0.001940995,0.0002131353,0.000008088171,0.0007206849,0.00005077865,0.00005628553,0.9833829,0.0002493411,0.002043547,0.01056788],"study_design_scores_gemma":[0.0002470382,0.002026729,0.1460353,0.00009733902,0.00006735716,0.007241245,0.0005833647,0.001732409,0.7939415,0.0006265437,0.04737505,0.00002613593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665128,0.01115364,0.004177483,0.001554066,0.0004421436,0.0001192898,0.002395875,0.0002955673,0.01334923],"genre_scores_gemma":[0.9690849,0.005066365,0.002059752,0.0005038847,0.0001630964,0.0001293478,0.002624712,0.00004984825,0.02031815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006241818,"threshold_uncertainty_score":0.020881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03971138302073033,"score_gpt":0.3450460202357461,"score_spread":0.3053346372150157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}