{"id":"W4389227919","doi":"10.1158/2326-6074.tumimm23-a026","title":"Abstract A026: Administration of preoperative ketorolac prevents osteosarcoma recurrence by promoting T cell memory and inhibiting immunosuppression","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ketorolac; Medicine; Immune system; Immunosuppression; Osteosarcoma; Cyclooxygenase; Metastasis; Immunotherapy; Cancer; Immunology; Pharmacology; Cancer research; Internal medicine; Biology; Analgesic","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002344375,0.0001640002,0.0003383684,0.0002333002,0.0002585369,0.0000224449,0.0001451034,0.0002253177,0.0001187298],"category_scores_gemma":[0.0006017686,0.0001439079,0.00004738858,0.0003391704,0.0003939983,0.000172331,0.0001978283,0.0008503227,0.00003043386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001105978,"about_ca_system_score_gemma":0.0004844918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000857971,"about_ca_topic_score_gemma":0.000006809363,"domain_scores_codex":[0.9976937,0.0005039799,0.0004344383,0.0003965358,0.0004284631,0.0005428661],"domain_scores_gemma":[0.9986771,0.0005042301,0.0001655461,0.0002331639,0.0003091648,0.0001108342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006849086,0.0001006417,0.01273055,0.0008489978,0.00005137302,0.00005519496,0.002287422,6.628989e-7,0.9578449,0.000006535203,0.001310801,0.024078],"study_design_scores_gemma":[0.001413992,0.0009131313,0.08108328,0.001102713,0.00001765415,0.00002261281,0.001031515,0.0002228842,0.9137926,0.00002243949,0.0002540986,0.000123117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916696,0.00577133,0.000001230308,0.0003401806,0.0001950613,0.001032908,0.00003047938,0.00005250607,0.0009066964],"genre_scores_gemma":[0.997655,0.001055597,0.0000226763,0.0000116039,0.00009945668,0.0002699397,0.00006640024,0.00002759841,0.0007917293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06835274,"threshold_uncertainty_score":0.5868393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03980411047910442,"score_gpt":0.3754176781044063,"score_spread":0.3356135676253019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}