{"id":"W4389227931","doi":"10.1158/2326-6074.tumimm23-b008","title":"Abstract B008: GPR64-targeting single-domain CAR-T cells for immunotherapy in Ewing sarcoma","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immunotherapy; Cancer research; Cancer; FLI1; Context (archaeology); Transcriptome; Medicine; Sarcoma; Mesenchymal stem cell; Cancer immunotherapy; Biology; Computational biology; Bioinformatics; Transcription factor; Internal medicine; Pathology; Gene expression; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001571597,0.0002616923,0.0003430734,0.0002794927,0.0001347267,0.0003063903,0.0001855522,0.0004217105,0.002801421],"category_scores_gemma":[0.00008624794,0.00008919602,0.0003204929,0.000260079,0.0001354765,0.0001791019,0.0002494705,0.0005889582,0.001051207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001985401,"about_ca_system_score_gemma":0.000166544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002113317,"about_ca_topic_score_gemma":0.0002023122,"domain_scores_codex":[0.9998875,0.00001390163,0.000006889924,0.00002966516,0.00003022741,0.000031793],"domain_scores_gemma":[0.999977,0.000002528215,0.000004338245,0.000002465244,0.000005216514,0.000008507887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003316935,0.00008868966,0.0003647903,0.00009205034,0.00001361641,0.00008485689,0.00001560617,0.0002227481,0.9909961,0.0001322338,0.0005745487,0.007083183],"study_design_scores_gemma":[0.0001901642,0.002605819,0.009126532,0.00002971033,0.000118304,0.001252323,0.00007785648,0.00465398,0.9553671,0.0002899862,0.02626971,0.00001835608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873521,0.00399577,0.004078636,0.0003226713,0.0001424534,0.0001330269,0.001250899,0.0002273834,0.002497071],"genre_scores_gemma":[0.9864608,0.00168308,0.004201008,0.0002308116,0.00003232326,0.0001532723,0.002824622,0.00003853821,0.004375632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002801421,"threshold_uncertainty_score":0.009371698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1201073928782566,"score_gpt":0.4206215850416921,"score_spread":0.3005141921634354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}