{"id":"W4389230816","doi":"10.1182/blood-2023-188739","title":"Treatment of Bleeding Episodes with Efanesoctocog Alfa in Children with Severe Hemophilia A in the XTEND-Kids Phase 3 Study","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Internal medicine; Von Willebrand factor; Surgery; Gastroenterology; Pediatrics; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001040337,0.0006543414,0.001055397,0.0001909251,0.0002517322,0.0007111704,0.0004216575,0.0005762033,0.002543573],"category_scores_gemma":[0.0005264374,0.0002131107,0.001458538,0.0001939872,0.0003778918,0.0003480646,0.000290782,0.001556184,0.0002927054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004659929,"about_ca_system_score_gemma":0.0009696882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000661432,"about_ca_topic_score_gemma":0.001515869,"domain_scores_codex":[0.999705,0.0001445322,0.00002231107,0.00003689459,0.00003574484,0.00005544596],"domain_scores_gemma":[0.999678,0.00006168264,0.00008434323,0.00001988835,0.00002368359,0.0001323798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5665657,0.03500482,0.05124253,0.004894097,0.004825761,0.001861564,0.0006429958,0.002751901,0.02500409,0.001400537,0.01529945,0.2905065],"study_design_scores_gemma":[0.44103,0.4197134,0.09459484,0.0006521951,0.002438121,0.003535198,0.0002495551,0.00117095,0.007286192,0.0003781429,0.02887957,0.00007178571],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977647,0.01377351,0.0007611594,0.0005853182,0.000144502,0.001861618,0.002204289,0.00007326469,0.00294929],"genre_scores_gemma":[0.9764825,0.009109162,0.0034244,0.001118187,0.0001910682,0.002715061,0.004378703,0.00002644004,0.002554484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002543573,"threshold_uncertainty_score":0.008509099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03127421053550209,"score_gpt":0.3311010903934329,"score_spread":0.2998268798579308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}