{"id":"W4389231019","doi":"10.1182/blood-2023-191011","title":"Acute Myeloid Leukemia (AML) Patients with Myelodysplasia (MDS) Related-Gene Mutations in First Complete Remission (CR1) Found to Have Benefit from Allogeneic Hematopoietic Stem Cell Transplant (HCT)","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Princess Margaret Cancer Centre; University of British Columbia; University Health Network","funders":"","keywords":"Internal medicine; Medicine; Oncology; Myelodysplastic syndromes; Myeloid leukemia; International Prognostic Scoring System; Transplantation; Gene mutation; Myeloid; Leukemia; Hematopoietic stem cell transplantation; Mutation; Gene; Bone marrow; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004248595,0.0002388005,0.0005835073,0.0002942373,0.0002440487,0.0002522016,0.0001931481,0.0003382878,0.001394491],"category_scores_gemma":[0.0008325367,0.00007211061,0.0003643474,0.0003013754,0.0001637115,0.0002439991,0.0002563093,0.0003327683,0.0001525606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002379777,"about_ca_system_score_gemma":0.000265226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003451058,"about_ca_topic_score_gemma":0.0005456728,"domain_scores_codex":[0.9997727,0.00004471686,0.00002067544,0.0000728993,0.00004300386,0.00004606449],"domain_scores_gemma":[0.9995753,0.0001216876,0.0001130591,0.00003308976,0.00003415112,0.0001225865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03790035,0.001035658,0.8740333,0.000325394,0.0004404534,0.001274131,0.0002189815,0.000929904,0.02691083,0.0002426664,0.0005226305,0.05616568],"study_design_scores_gemma":[0.0004243774,0.008467341,0.9837715,0.00001955803,0.0003508884,0.001785113,0.00005925795,0.0005196782,0.002310811,0.000128562,0.002152179,0.00001070357],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983593,0.0007353463,0.0001478767,0.00002360489,0.00001075892,0.00003157874,0.0002331164,0.000005918261,0.000452652],"genre_scores_gemma":[0.9987124,0.0001370811,0.0001669061,0.00002430468,0.00001888301,0.00002224963,0.0006972132,0.000001534571,0.0002194287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001394491,"threshold_uncertainty_score":0.004665017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01521623447456265,"score_gpt":0.2416126413420736,"score_spread":0.226396406867511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}