{"id":"W4389231136","doi":"10.1182/blood-2023-189154","title":"Frailty Impact on Outcomes of Patients Undergoing Chimeric Antigen Receptor T-Cell (CAR T) Therapy at Princess Margaret Cancer Centre: A Prospective Pilot Study","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Frailty in Older Adults","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Chimeric antigen receptor; Cohort; Hematopoietic stem cell transplantation; Prospective cohort study; Diffuse large B-cell lymphoma; Follicular lymphoma; Cancer; Oncology; Lymphoma; Transplantation; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007122732,0.0002782654,0.0002940082,0.000648985,0.0006688958,0.0006256901,0.0002784891,0.0003116341,0.001191902],"category_scores_gemma":[0.001914127,0.0001951014,0.0004986148,0.0006544355,0.000373718,0.0004219301,0.0005734234,0.0004015727,0.0002347174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006704301,"about_ca_system_score_gemma":0.0006395287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01351483,"about_ca_topic_score_gemma":0.01370379,"domain_scores_codex":[0.9995883,0.0001013099,0.00003286379,0.00007568767,0.0000753706,0.0001263634],"domain_scores_gemma":[0.9986047,0.000155453,0.000531537,0.00006849694,0.000178666,0.0004610882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004956459,0.0001711283,0.9976471,0.000006979988,0.00002733101,0.00008130312,0.0001393155,0.00003205648,0.0001170266,0.000006213745,0.0000700039,0.001205984],"study_design_scores_gemma":[0.00002663058,0.001220526,0.998198,0.000004556211,0.00002041025,0.0001320608,0.0001700682,0.00007772482,0.00003425387,0.000006592373,0.0001052518,0.000003932445],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996998,0.00004440813,0.00001250437,0.000009963032,0.000001135997,0.00001764433,0.00009395824,5.047033e-7,0.000119996],"genre_scores_gemma":[0.9996316,0.0000349024,0.00002300244,0.00001691176,0.000005180421,0.00001936995,0.0001850119,4.153376e-7,0.00008355779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01351483,"threshold_uncertainty_score":0.02687234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03053630550127311,"score_gpt":0.3099652461533629,"score_spread":0.2794289406520898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}