{"id":"W4389231884","doi":"10.1182/blood-2023-179474","title":"TRANSCEND FL: Phase 2 Study Primary Analysis of Lisocabtagene Maraleucel as Second-Line Therapy in Patients with High-Risk Relapsed or Refractory Follicular Lymphoma","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Follicular lymphoma; Refractory (planetary science); Clinical endpoint; Oncology; Cohort; Phases of clinical research; Lymphoma; Gastroenterology; Surgery; Chemotherapy; Clinical trial; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002160969,0.001437263,0.001653478,0.0004083301,0.0003349386,0.001159127,0.0008895476,0.0009597995,0.006309181],"category_scores_gemma":[0.001000276,0.0005405307,0.001638181,0.0003252941,0.0005347749,0.0007327701,0.0004574777,0.00219664,0.001198744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009373316,"about_ca_system_score_gemma":0.001538432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006056068,"about_ca_topic_score_gemma":0.002274073,"domain_scores_codex":[0.9994942,0.0002303215,0.00002162629,0.0001094666,0.00005952312,0.00008478276],"domain_scores_gemma":[0.9993427,0.00008978567,0.0001717062,0.00006288713,0.00008073126,0.0002521891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7571496,0.04327135,0.01909637,0.002704472,0.005464007,0.0004696774,0.0003466192,0.002574883,0.0614532,0.000487305,0.01391809,0.09306437],"study_design_scores_gemma":[0.5820113,0.3545759,0.03530012,0.0001488158,0.003843038,0.001145993,0.0001347177,0.001934337,0.008097389,0.0004345914,0.01230017,0.00007362876],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729366,0.00503999,0.00136733,0.0007498901,0.0001725093,0.007134201,0.007731528,0.0002680956,0.004599909],"genre_scores_gemma":[0.9726917,0.002177088,0.002327872,0.001575364,0.0002924054,0.005797155,0.01066972,0.0000902924,0.004378321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006309181,"threshold_uncertainty_score":0.0211063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02043691441757153,"score_gpt":0.2999379315298334,"score_spread":0.2795010171122619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}